IHFA_SALPK
ID IHFA_SALPK Reviewed; 99 AA.
AC B5BA36;
DT 14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Integration host factor subunit alpha {ECO:0000255|HAMAP-Rule:MF_00380};
DE Short=IHF-alpha {ECO:0000255|HAMAP-Rule:MF_00380};
GN Name=ihfA {ECO:0000255|HAMAP-Rule:MF_00380};
GN Synonyms=himA {ECO:0000255|HAMAP-Rule:MF_00380};
GN OrderedLocusNames=SSPA1396;
OS Salmonella paratyphi A (strain AKU_12601).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=554290;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AKU_12601;
RX PubMed=19159446; DOI=10.1186/1471-2164-10-36;
RA Holt K.E., Thomson N.R., Wain J., Langridge G.C., Hasan R., Bhutta Z.A.,
RA Quail M.A., Norbertczak H., Walker D., Simmonds M., White B., Bason N.,
RA Mungall K., Dougan G., Parkhill J.;
RT "Pseudogene accumulation in the evolutionary histories of Salmonella
RT enterica serovars Paratyphi A and Typhi.";
RL BMC Genomics 10:36-36(2009).
CC -!- FUNCTION: This protein is one of the two subunits of integration host
CC factor, a specific DNA-binding protein that functions in genetic
CC recombination as well as in transcriptional and translational control.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
CC -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000255|HAMAP-
CC Rule:MF_00380}.
CC -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC {ECO:0000255|HAMAP-Rule:MF_00380}.
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DR EMBL; FM200053; CAR59575.1; -; Genomic_DNA.
DR RefSeq; WP_001229266.1; NC_011147.1.
DR AlphaFoldDB; B5BA36; -.
DR SMR; B5BA36; -.
DR GeneID; 66755750; -.
DR KEGG; sek:SSPA1396; -.
DR HOGENOM; CLU_105066_1_3_6; -.
DR OMA; IYVRGFG; -.
DR Proteomes; UP000001869; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd13835; IHF_A; 1.
DR Gene3D; 4.10.520.10; -; 1.
DR HAMAP; MF_00380; IHF_alpha; 1.
DR InterPro; IPR000119; Hist_DNA-bd.
DR InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR InterPro; IPR005684; IHF_alpha.
DR PANTHER; PTHR33175; PTHR33175; 1.
DR Pfam; PF00216; Bac_DNA_binding; 1.
DR PRINTS; PR01727; DNABINDINGHU.
DR SMART; SM00411; BHL; 1.
DR SUPFAM; SSF47729; SSF47729; 1.
DR TIGRFAMs; TIGR00987; himA; 1.
DR PROSITE; PS00045; HISTONE_LIKE; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW Translation regulation.
FT CHAIN 1..99
FT /note="Integration host factor subunit alpha"
FT /id="PRO_1000122165"
FT REGION 49..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 99 AA; 11368 MW; 278B782BCD79D754 CRC64;
MALTKAEMSE YLFDKLGLSK RDAKELVELF FEEIRRALEN GEQVKLSGFG NFDLRDKNQR
PGRNPKTGED IPITARRVVT FRPGQKLKSR VENASPKEE