ID   IHFA_SERMA              Reviewed;          99 AA.
AC   P23302;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=himA;
OS   Serratia marcescens.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1917861; DOI=10.1128/jb.173.19.6297-6299.1991;
RA   Haluzi H., Goitein D., Koby S., Mendelson I., Teff D., Mengeritsky G.,
RA   Giladi H., Oppenheim A.B.;
RT   "Genes coding for integration host factor are conserved in Gram-negative
RT   bacteria.";
RL   J. Bacteriol. 173:6297-6299(1991).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; M62644; AAA26558.1; -; Genomic_DNA.
DR   PIR; A38173; A38173.
DR   AlphaFoldDB; P23302; -.
DR   SMR; P23302; -.
DR   STRING; 273526.SMDB11_1423; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..99
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105027"
FT   REGION          49..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   99 AA;  11256 MW;  778A8AFF9BEBD8BA CRC64;
     MALTKAEMSE HLFEKLGLSK RDAKDLVELF FEEVRRALEN GEQVKLSGFG NFDLRDKNQR
     PGRNPKTGED IPITARRVVT FRPGQKLKSR VENASPKGE