ID   IHFA_THIDA              Reviewed;         103 AA.
AC   Q3SK28;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Integration host factor subunit alpha {ECO:0000255|HAMAP-Rule:MF_00380};
DE            Short=IHF-alpha {ECO:0000255|HAMAP-Rule:MF_00380};
GN   Name=ihfA {ECO:0000255|HAMAP-Rule:MF_00380};
GN   Synonyms=himA {ECO:0000255|HAMAP-Rule:MF_00380};
GN   OrderedLocusNames=Tbd_1013;
OS   Thiobacillus denitrificans (strain ATCC 25259).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Thiobacillaceae; Thiobacillus.
OX   NCBI_TaxID=292415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25259;
RX   PubMed=16452431; DOI=10.1128/jb.188.4.1473-1488.2006;
RA   Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W.,
RA   Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.;
RT   "The genome sequence of the obligately chemolithoautotrophic, facultatively
RT   anaerobic bacterium Thiobacillus denitrificans.";
RL   J. Bacteriol. 188:1473-1488(2006).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000255|HAMAP-Rule:MF_00380}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain. {ECO:0000255|HAMAP-
CC       Rule:MF_00380}.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_00380}.
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DR   EMBL; CP000116; AAZ96966.1; -; Genomic_DNA.
DR   RefSeq; WP_011311525.1; NC_007404.1.
DR   AlphaFoldDB; Q3SK28; -.
DR   SMR; Q3SK28; -.
DR   STRING; 292415.Tbd_1013; -.
DR   EnsemblBacteria; AAZ96966; AAZ96966; Tbd_1013.
DR   KEGG; tbd:Tbd_1013; -.
DR   eggNOG; COG0776; Bacteria.
DR   HOGENOM; CLU_105066_1_0_4; -.
DR   OMA; IYVRGFG; -.
DR   OrthoDB; 1847472at2; -.
DR   Proteomes; UP000008291; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation; Translation regulation.
FT   CHAIN           1..103
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000277785"
FT   REGION          55..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   103 AA;  11532 MW;  EBF234EB531068D1 CRC64;
     MTTLTKADLA ELLFEKVGLN KREAKDVVES FFDEIRLALE KGDIVKLSGF GNFQCREKPQ
     RPGRNPKTGE EMPISARRVV TFHASQKLKS QVEGARIGTP SQE