ID   IHFA_YERPS              Reviewed;          98 AA.
AC   Q9X9F6; Q669Z7;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 2.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Integration host factor subunit alpha;
DE            Short=IHF-alpha;
GN   Name=ihfA; Synonyms=hid, himA; OrderedLocusNames=YPTB2335;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Simonet M., Devalckenaere A., Odaert M., Trieu-Cuot P.;
RT   "Characterization of IS1541-like elements in Yersinia enterocolitica and
RT   Yersinia pseudotuberculosis.";
RL   Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: This protein is one of the two subunits of integration host
CC       factor, a specific DNA-binding protein that functions in genetic
CC       recombination as well as in transcriptional and translational control.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of an alpha and a beta chain.
CC   -!- SIMILARITY: Belongs to the bacterial histone-like protein family.
CC       {ECO:0000305}.
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DR   EMBL; AJ238013; CAB46606.1; -; Genomic_DNA.
DR   EMBL; BX936398; CAH21573.1; -; Genomic_DNA.
DR   RefSeq; WP_002211830.1; NZ_CP009712.1.
DR   AlphaFoldDB; Q9X9F6; -.
DR   SMR; Q9X9F6; -.
DR   EnsemblBacteria; CAH21573; CAH21573; YPTB2335.
DR   GeneID; 61908091; -.
DR   GeneID; 67418158; -.
DR   KEGG; ypo:BZ17_119; -.
DR   KEGG; yps:YPTB2335; -.
DR   PATRIC; fig|273123.14.peg.128; -.
DR   OMA; IYVRGFG; -.
DR   Proteomes; UP000001011; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0030527; F:structural constituent of chromatin; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR   CDD; cd13835; IHF_A; 1.
DR   Gene3D; 4.10.520.10; -; 1.
DR   HAMAP; MF_00380; IHF_alpha; 1.
DR   InterPro; IPR000119; Hist_DNA-bd.
DR   InterPro; IPR020816; Histone-like_DNA-bd_CS.
DR   InterPro; IPR010992; IHF-like_DNA-bd_dom_sf.
DR   InterPro; IPR005684; IHF_alpha.
DR   PANTHER; PTHR33175; PTHR33175; 1.
DR   Pfam; PF00216; Bac_DNA_binding; 1.
DR   PRINTS; PR01727; DNABINDINGHU.
DR   SMART; SM00411; BHL; 1.
DR   SUPFAM; SSF47729; SSF47729; 1.
DR   TIGRFAMs; TIGR00987; himA; 1.
DR   PROSITE; PS00045; HISTONE_LIKE; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Transcription; Transcription regulation;
KW   Translation regulation.
FT   CHAIN           1..98
FT                   /note="Integration host factor subunit alpha"
FT                   /id="PRO_0000105038"
FT   REGION          49..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        20..25
FT                   /note="KRDAKD -> NEMLKI (in Ref. 1; CAB46606)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   98 AA;  11186 MW;  89EAFF9FFBC94A15 CRC64;
     MALTKAEMSE HLFEKLGLSK RDAKDLVELF FEEVRRALEN GEQVKLSGFG NFDLRDKNQR
     PGRNPKTGED IPITARRVVT FRPGQKLKSR VESATPKE