ID   1104B_ASFL5             Reviewed;         124 AA.
AC   P26708;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   03-AUG-2022, entry version 47.
DE   RecName: Full=Protein MGF 110-4L-B;
DE   Flags: Precursor;
GN   ORFNames=LIS124-2;
OS   African swine fever virus (isolate Portugal/Lis 57/1957) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10499;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2219721; DOI=10.1016/0042-6822(90)90293-z;
RA   de la Vega I., Vinuela E., Blasco R.;
RT   "Genetic variation and multigene families in African swine fever virus.";
RL   Virology 179:234-246(1990).
CC   -!- FUNCTION: Causes the redistribution of lumenal ER protein to an
CC       enlarged ERGIC compartment. {ECO:0000250|UniProtKB:P18558}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P18558}. Host
CC       endoplasmic reticulum-Golgi intermediate compartment
CC       {ECO:0000250|UniProtKB:P18558}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR   EMBL; M58155; AAA42717.1; -; Genomic_DNA.
DR   PIR; B36821; B36821.
DR   GO; GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004848; ASFV_fam_110.
DR   Pfam; PF01639; v110; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein; Signal; Virion.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..124
FT                   /note="Protein MGF 110-4L-B"
FT                   /id="PRO_0000036738"
FT   MOTIF           121..124
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000250|UniProtKB:P18558"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  14170 MW;  74DC0975610ABF45 CRC64;
     MLVIFLGILG LLANQVLGLP TQAGGHLRST DNPPQEELGY WCTYMESCKF CWACAHGICK
     NKVNMSMPLI IENSYLTSCE VSRWYNQCTY SEGNGHYHVM DCSDPVPHNR PHRLLMKIYE
     KEDL