ID   IKBP1_DANRE             Reviewed;         249 AA.
AC   Q501X6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-JUN-2005, sequence version 1.
DT   03-AUG-2022, entry version 65.
DE   RecName: Full=Interleukin-1 receptor-associated kinase 1-binding protein 1 homolog;
GN   Name=irak1bp1; ORFNames=zgc:112481;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be part of a signaling pathway that leads to NF-kappa-B
CC       activation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRAK1BP1 family. {ECO:0000305}.
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DR   EMBL; BC095828; AAH95828.1; -; mRNA.
DR   RefSeq; NP_001018607.1; NM_001020771.1.
DR   AlphaFoldDB; Q501X6; -.
DR   SMR; Q501X6; -.
DR   STRING; 7955.ENSDARP00000053587; -.
DR   PaxDb; Q501X6; -.
DR   GeneID; 553809; -.
DR   KEGG; dre:553809; -.
DR   CTD; 134728; -.
DR   ZFIN; ZDB-GENE-050522-272; irak1bp1.
DR   eggNOG; ENOG502QVHT; Eukaryota.
DR   InParanoid; Q501X6; -.
DR   OrthoDB; 1445231at2759; -.
DR   PhylomeDB; Q501X6; -.
DR   PRO; PR:Q501X6; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IBA:GO_Central.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   InterPro; IPR007497; DUF541.
DR   InterPro; IPR030312; IRAK1BP1.
DR   PANTHER; PTHR18842; PTHR18842; 1.
DR   Pfam; PF04402; SIMPL; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..249
FT                   /note="Interleukin-1 receptor-associated kinase 1-binding
FT                   protein 1 homolog"
FT                   /id="PRO_0000313735"
SQ   SEQUENCE   249 AA;  28063 MW;  0AE8F9D54A27A1FF CRC64;
     MAHSPSRVFA ALSPSAGDVY RDENQSVFNR GRKQTHLSAQ SNVRVIEVTG CAEISSPPDR
     ACVSISVKNS KENVNDVTNS VTRRLEYILQ TARQHDVKEE NITVTKHLQR DEDLFHMQAE
     VLVVFLDFEK MQQARTVLIE KLDKSVCVGD PYYSHSAESL SLLRRRVCLE AVDNARLKAS
     EACCTLGQAL GRPLLVREEE SREWSSSQQD ASGSPLTLHP RTDATLISAT SRMFVTFELR
     PKDNNRRKF