ID   IKBP1_XENLA             Reviewed;         245 AA.
AC   Q08AV8;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Interleukin-1 receptor-associated kinase 1-binding protein 1 homolog;
GN   Name=irak1bp1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be part of a signaling pathway that leads to NF-kappa-B
CC       activation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IRAK1BP1 family. {ECO:0000305}.
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DR   EMBL; BC124989; AAI24990.1; -; mRNA.
DR   RefSeq; NP_001121320.1; NM_001127848.1.
DR   AlphaFoldDB; Q08AV8; -.
DR   SMR; Q08AV8; -.
DR   DNASU; 100158405; -.
DR   GeneID; 100158405; -.
DR   KEGG; xla:100158405; -.
DR   CTD; 100158405; -.
DR   Xenbase; XB-GENE-960911; irak1bp1.S.
DR   OMA; TQTATRE; -.
DR   OrthoDB; 1445231at2759; -.
DR   Proteomes; UP000186698; Chromosome 5S.
DR   Bgee; 100158405; Expressed in testis and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   InterPro; IPR007497; DUF541.
DR   InterPro; IPR030312; IRAK1BP1.
DR   PANTHER; PTHR18842; PTHR18842; 1.
DR   Pfam; PF04402; SIMPL; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..245
FT                   /note="Interleukin-1 receptor-associated kinase 1-binding
FT                   protein 1 homolog"
FT                   /id="PRO_0000313737"
SQ   SEQUENCE   245 AA;  26808 MW;  3B9EDFE58BA1BC5D CRC64;
     MAATSPVSRI FASLQPANSS ALHTGDLENR AGIVVGQHGG REVQVSGSAE LSAAPDRAQV
     CIAVSSSKGT AAEAKSSVQR RLEYIAQSLR QGGVTEENIT VSKEFQRLSN TYKMEAVVCV
     VFSDFDKLQS NCNLLVEKLD SSVNISPPHF YHTADCLEKL RREVCLGAVA NARRKAQEVC
     RLVGHSLGKA LIIREEELRE WEDQAESSQA HQSIQSKIKT ATIYAASKIL ATFEIKGKER
     HKKNR