ID   APL_LACLM               Reviewed;         214 AA.
AC   Q48630; A2RM98;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 2.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Alkaline phosphatase-like protein;
GN   Name=apl; OrderedLocusNames=llmg_1854;
OS   Lactococcus lactis subsp. cremoris (strain MG1363).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus; Lactococcus cremoris subsp. cremoris.
OX   NCBI_TaxID=416870;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Venema K., Haandrikman A., Leenhouts K., Kok J., Venema G.;
RT   "Cloning and sequencing of a gene (apl) from Lactococcus lactis that can
RT   complement a phoA mutation in Escherichia coli.";
RL   Submitted (DEC-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MG1363;
RX   PubMed=17307855; DOI=10.1128/jb.01768-06;
RA   Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C.,
RA   Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P.,
RA   van Sinderen D., Kok J.;
RT   "The complete genome sequence of the lactic acid bacterial paradigm
RT   Lactococcus lactis subsp. cremoris MG1363.";
RL   J. Bacteriol. 189:3256-3270(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DedA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA82306.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; Z29065; CAA82306.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AM406671; CAL98425.1; -; Genomic_DNA.
DR   PIR; S39339; S39339.
DR   RefSeq; WP_011835619.1; NZ_WJVF01000021.1.
DR   AlphaFoldDB; Q48630; -.
DR   STRING; 416870.llmg_1854; -.
DR   EnsemblBacteria; CAL98425; CAL98425; llmg_1854.
DR   GeneID; 61108971; -.
DR   KEGG; llm:llmg_1854; -.
DR   eggNOG; COG0586; Bacteria.
DR   HOGENOM; CLU_044208_1_1_9; -.
DR   OMA; SNARFQF; -.
DR   PhylomeDB; Q48630; -.
DR   BioCyc; LLAC416870:LLMG_RS09290-MON; -.
DR   Proteomes; UP000000364; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR032816; SNARE_assoc.
DR   Pfam; PF09335; SNARE_assoc; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..214
FT                   /note="Alkaline phosphatase-like protein"
FT                   /id="PRO_0000161409"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   214 AA;  23760 MW;  8CC155CF4211CEDC CRC64;
     MQEIIIQVMN QFGYFGVAFL IMIENIFPPI PSEVILTFGG FMTTYSELGI IGMIIAATIG
     SVLGALILYF VGRLLSVERL ERLVSGRLGK VLRLKPEDIT KAEKWFLKRG YATIFFCRFI
     PLIRSLISVP AGSAKMKLPS FLILTTLGTL IWNIVLVSLG AALGDNWEMI AGILDSYSSV
     VVAILGVIFI LGLLLFVKKR FFPKNKNYSP DSEK