ID   IL17_SHV21              Reviewed;         151 AA.
AC   P24916;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   10-FEB-2021, entry version 87.
DE   RecName: Full=Viral interleukin-17;
DE            Short=vIL-17;
DE   AltName: Full=Immediate early gene 13 protein;
DE   Flags: Precursor;
GN   Name=13; Synonyms=KCLF2;
OS   Saimiriine herpesvirus 2 (strain 11) (SaHV-2) (Herpesvirus saimiri).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Rhadinovirus.
OX   NCBI_TaxID=10383;
OH   NCBI_TaxID=9521; Saimiri sciureus (Common squirrel monkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2154888; DOI=10.1016/0042-6822(90)90107-3;
RA   Albrecht J.-C., Fleckenstein B.;
RT   "Structural organization of the conserved gene block of Herpesvirus saimiri
RT   coding for DNA polymerase, glycoprotein B, and major DNA binding protein.";
RL   Virology 174:533-542(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1321287; DOI=10.1128/jvi.66.8.5047-5058.1992;
RA   Albrecht J.-C., Nicholas J., Biller D., Cameron K.R., Biesinger B.,
RA   Newman C., Wittmann S., Craxton M.A., Coleman H., Fleckenstein B.,
RA   Honess R.W.;
RT   "Primary structure of the herpesvirus saimiri genome.";
RL   J. Virol. 66:5047-5058(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1699352; DOI=10.1016/0042-6822(90)90288-3;
RA   Nicholas J., Smith E.P., Coles L., Honess R.;
RT   "Gene expression in cells infected with gammaherpesvirus saimiri:
RT   properties of transcripts from two immediate-early genes.";
RL   Virology 179:189-200(1990).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the IL-17 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X64346; CAA45636.1; -; Genomic_DNA.
DR   EMBL; M31122; AAA46169.1; -; Genomic_DNA.
DR   EMBL; M60286; AAA46156.1; -; Genomic_DNA.
DR   RefSeq; NP_040215.1; NC_001350.1.
DR   SMR; P24916; -.
DR   GeneID; 1682476; -.
DR   KEGG; vg:1682476; -.
DR   Proteomes; UP000000587; Genome.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR   GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.90.10; -; 1.
DR   InterPro; IPR029034; Cystine-knot_cytokine.
DR   InterPro; IPR020440; IL-17_chr.
DR   InterPro; IPR010345; IL-17_fam.
DR   Pfam; PF06083; IL17; 1.
DR   PRINTS; PR01932; INTRLEUKIN17.
DR   SUPFAM; SSF57501; SSF57501; 1.
PE   3: Inferred from homology;
KW   Cytokine; Disulfide bond; Early protein; Glycoprotein; Reference proteome;
KW   Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..151
FT                   /note="Viral interleukin-17"
FT                   /id="PRO_0000015433"
FT   CARBOHYD        36
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        53
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        64
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
FT   DISULFID        90..140
FT                   /evidence="ECO:0000250"
FT   DISULFID        95..142
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   151 AA;  17180 MW;  53BEDDE4206C6432 CRC64;
     MTFRMTSLVL LLLLSIDCIV KSEITSAQTP RCLAANNSFP RSVMVTLSIR NWNTSSKRAS
     DYYNRSTSPW TLHRNEDQDR YPSVIWEAKC RYLGCVNADG NVDYHMNSVP IQQEILVVRK
     GHQPCPNSFR LEKMLVTVGC TCVTPIVHNV D