ID   ILF2_DANRE              Reviewed;         387 AA.
AC   Q6NZ06;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Interleukin enhancer-binding factor 2 homolog;
GN   Name=ilf2;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Appears to function predominantly as a heterodimeric complex
CC       with ILF3. This complex may function to regulate transcription of
CC       undefined genes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Forms heterodimers with ILF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; BC066394; AAH66394.1; -; mRNA.
DR   EMBL; BC059456; AAH59456.1; -; mRNA.
DR   RefSeq; NP_998401.1; NM_213236.2.
DR   AlphaFoldDB; Q6NZ06; -.
DR   SMR; Q6NZ06; -.
DR   STRING; 7955.ENSDARP00000022486; -.
DR   PaxDb; Q6NZ06; -.
DR   PRIDE; Q6NZ06; -.
DR   Ensembl; ENSDART00000018255; ENSDARP00000022486; ENSDARG00000014591.
DR   GeneID; 406517; -.
DR   KEGG; dre:406517; -.
DR   CTD; 3608; -.
DR   ZFIN; ZDB-GENE-040426-2345; ilf2.
DR   eggNOG; KOG3793; Eukaryota.
DR   GeneTree; ENSGT00940000154879; -.
DR   HOGENOM; CLU_064863_1_0_1; -.
DR   InParanoid; Q6NZ06; -.
DR   OMA; MEGDASY; -.
DR   OrthoDB; 1145212at2759; -.
DR   PhylomeDB; Q6NZ06; -.
DR   TreeFam; TF320194; -.
DR   Reactome; R-DRE-6798695; Neutrophil degranulation.
DR   PRO; PR:Q6NZ06; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 19.
DR   Bgee; ENSDARG00000014591; Expressed in mature ovarian follicle and 28 other tissues.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR006561; DZF_dom.
DR   InterPro; IPR043519; NT_sf.
DR   Pfam; PF07528; DZF; 1.
DR   SMART; SM00572; DZF; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
DR   PROSITE; PS51703; DZF; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..387
FT                   /note="Interleukin enhancer-binding factor 2 homolog"
FT                   /id="PRO_0000126067"
FT   DOMAIN          24..371
FT                   /note="DZF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01040"
FT   REGION          352..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..387
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   387 AA;  42852 MW;  D5DA736C05D5610C CRC64;
     MRGDRGRGRG GRFGSRGGLV QGYRPFVPHI PFDFYVCEMA FPRVKPASDE TAFSECLLKR
     NQDLSPTPSE QASILSLVTK INNVIDNLIV APGNFEVQIE EVRQVGSYKK GTMTAGHNVA
     DLVVILKILP TLEAVAALGN KVVETLRTQD PSEVLSMLTN ETGFEISSAD ATVKILITTV
     PPNLRKLDPE LHLDIKVLQS ALAAIRHARW FEENASQSTV KVLIRLLKDI RVRFPGFEPL
     TPWILDLLGH SAVMNHPSRQ PLPLNVAYRR CLQMLAAGLF LPGSVGITDP CESGNFRVHT
     VMTLEQQDMV CFTAQTLVRV LSHGGYRKIL GLEGDASYLT TEMSTWDGVI VTPSEKAYEK
     PPERKEEEDE ALEEGVEAED ESMETQE