ID   ILF2_XENTR              Reviewed;         388 AA.
AC   Q6P8G1; Q28DF3;
DT   12-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Interleukin enhancer-binding factor 2 homolog;
GN   Name=ilf2; ORFNames=TEgg021l09.1, TEgg033l23.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate transcription of undefined genes. {ECO:0000250}.
CC   -!- SUBUNIT: Forms heterodimers with ILF3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
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DR   EMBL; CR848422; CAJ81376.1; -; mRNA.
DR   EMBL; CR855547; CAJ81441.1; -; mRNA.
DR   EMBL; BC061266; AAH61266.1; -; mRNA.
DR   RefSeq; NP_988997.1; NM_203666.1.
DR   AlphaFoldDB; Q6P8G1; -.
DR   SMR; Q6P8G1; -.
DR   STRING; 8364.ENSXETP00000060958; -.
DR   DNASU; 394593; -.
DR   GeneID; 394593; -.
DR   KEGG; xtr:394593; -.
DR   CTD; 3608; -.
DR   Xenbase; XB-GENE-876477; ilf2.
DR   eggNOG; KOG3793; Eukaryota.
DR   InParanoid; Q6P8G1; -.
DR   Reactome; R-XTR-6798695; Neutrophil degranulation.
DR   Proteomes; UP000008143; Chromosome 8.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005730; C:nucleolus; ISS:UniProtKB.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; ISS:UniProtKB.
DR   GO; GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:UniProtKB.
DR   Gene3D; 3.30.460.10; -; 1.
DR   InterPro; IPR006561; DZF_dom.
DR   InterPro; IPR043519; NT_sf.
DR   Pfam; PF07528; DZF; 1.
DR   SMART; SM00572; DZF; 1.
DR   SUPFAM; SSF81301; SSF81301; 1.
DR   PROSITE; PS51703; DZF; 1.
PE   2: Evidence at transcript level;
KW   Activator; DNA-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..388
FT                   /note="Interleukin enhancer-binding factor 2 homolog"
FT                   /id="PRO_0000126068"
FT   DOMAIN          23..370
FT                   /note="DZF"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01040"
FT   REGION          349..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..370
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        371..388
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   388 AA;  42894 MW;  BF5AFBC5E2FB022C CRC64;
     MRGERGRGRG RFGSRVGPNT GFRPFVPHIP FDFHVCEMAF PRVKPAPDDS SFSESLLKRN
     QDLAPSTAEQ ASILSLVTKI NNVIDNLIVA PGNFEVQIEE VRQVGSYKKG TMSTGHNVAD
     LVVILKILPT LEAVSALGIK VVETLRTQDP AEVLTMLTNE TGFEISSADA TVKILITTVP
     PNLRKLDPEL HLDIKVLQSA LAAIRHARWF EENASHSTVK VLIRLLKDLR SRFPGFEPLT
     PWILDLLGHY AVMNNPTRQP LALNVSYKRC LQMLAAGLFL PGSVGITDPC ESGNFRVHTV
     MTLEQQDMVC YTAQTLVRIL SHGGFRKILG LEGDASALAT EMSTWDGVIV TPSEKAYEKP
     PERKEGEEDE NQDIPEGAEE EESMETQE