ID   ILI4_ORYSJ              Reviewed;          87 AA.
AC   Q0DDF6; A0A0P0WUS7;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Transcription factor ILI4;
DE            Short=OsILI4;
DE   AltName: Full=Basic helix-loop-helix protein 172;
DE            Short=OsbHLH172;
DE   AltName: Full=Protein BRASSINOSTEROID UPREGULATED 1;
DE   AltName: Full=Protein INCREASED LEAF INCLINATION 4;
DE   AltName: Full=bHLH transcription factor bHLH172;
GN   Name=ILI4; Synonyms=BHLH172, BU1;
GN   OrderedLocusNames=Os06g0226500, LOC_Os06g12210; ORFNames=OsJ_20669;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
RN   [6]
RP   FUNCTION, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX   PubMed=19648232; DOI=10.1104/pp.109.140806;
RA   Tanaka A., Nakagawa H., Tomita C., Shimatani Z., Ohtake M., Nomura T.,
RA   Jiang C.J., Dubouzet J.G., Kikuchi S., Sekimoto H., Yokota T., Asami T.,
RA   Kamakura T., Mori M.;
RT   "BRASSINOSTEROID UPREGULATED1, encoding a helix-loop-helix protein, is a
RT   novel gene involved in brassinosteroid signaling and controls bending of
RT   the lamina joint in rice.";
RL   Plant Physiol. 151:669-680(2009).
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20472752; DOI=10.1104/pp.110.153593;
RA   Carretero-Paulet L., Galstyan A., Roig-Villanova I., Martinez-Garcia J.F.,
RA   Bilbao-Castro J.R., Robertson D.L.;
RT   "Genome-wide classification and evolutionary analysis of the bHLH family of
RT   transcription factors in Arabidopsis, poplar, rice, moss, and algae.";
RL   Plant Physiol. 153:1398-1412(2010).
CC   -!- FUNCTION: Atypical and probable non DNA-binding bHLH transcription
CC       factor that acts as a positive regulator of brassinsteroid (BR)
CC       response. Controls lamina inclination by participating in two BR
CC       signaling pathways involving BRI1 and RGA1.
CC       {ECO:0000269|PubMed:19648232}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305|PubMed:19648232}.
CC   -!- TISSUE SPECIFICITY: Expressed in phloem of leaf blades and sheaths,
CC       lamina joints, filaments before anthesis, vasculare bundles of the
CC       ovule, lemma and palea, and embryos. {ECO:0000269|PubMed:19648232}.
CC   -!- INDUCTION: By brassinolide. Repressed by abscisic acid (ABA).
CC       {ECO:0000269|PubMed:19648232}.
CC   -!- MISCELLANEOUS: Plants over-expressing ILI4 show enhanced bending of the
CC       lamina joint, increased grain size and resistance to brassinazole, an
CC       inhibitor of BR biosynthesis. {ECO:0000305|PubMed:19648232}.
CC   -!- SIMILARITY: Belongs to the bHLH protein family.
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DR   EMBL; AP008212; BAF19117.1; -; Genomic_DNA.
DR   EMBL; AP014962; BAS96875.1; -; Genomic_DNA.
DR   EMBL; CM000143; EAZ36342.1; -; Genomic_DNA.
DR   EMBL; AK071601; BAG92577.1; -; mRNA.
DR   RefSeq; XP_015642646.1; XM_015787160.1.
DR   AlphaFoldDB; Q0DDF6; -.
DR   SMR; Q0DDF6; -.
DR   STRING; 4530.OS06T0226500-01; -.
DR   PaxDb; Q0DDF6; -.
DR   PRIDE; Q0DDF6; -.
DR   EnsemblPlants; Os06t0226500-01; Os06t0226500-01; Os06g0226500.
DR   GeneID; 4340551; -.
DR   Gramene; Os06t0226500-01; Os06t0226500-01; Os06g0226500.
DR   KEGG; osa:4340551; -.
DR   eggNOG; ENOG502SURH; Eukaryota.
DR   HOGENOM; CLU_183267_0_0_1; -.
DR   InParanoid; Q0DDF6; -.
DR   OMA; IPHSHSH; -.
DR   OrthoDB; 1589357at2759; -.
DR   Proteomes; UP000000763; Chromosome 6.
DR   Proteomes; UP000007752; Chromosome 6.
DR   Proteomes; UP000059680; Chromosome 6.
DR   Genevisible; Q0DDF6; OS.
DR   GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0009742; P:brassinosteroid mediated signaling pathway; IEA:UniProtKB-KW.
DR   GO; GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   GO; GO:0009741; P:response to brassinosteroid; IMP:UniProtKB.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR044293; PRE.
DR   PANTHER; PTHR46446; PTHR46446; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   2: Evidence at transcript level;
KW   Brassinosteroid signaling pathway; Cytoplasm; Growth regulation;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..87
FT                   /note="Transcription factor ILI4"
FT                   /id="PRO_0000429094"
FT   DOMAIN          1..54
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ   SEQUENCE   87 AA;  9747 MW;  79E83DA700193F5A CRC64;
     MSSRRSSRSS VSEEEINELI SKLQSLLPSS RRRGANQAST TKLLKETCSY IKSLHREVDD
     LSDRLSDLMA GMDHNSPGAE IIRSLLR