ID   ILI5_ORYSJ              Reviewed;          88 AA.
AC   Q6YUX0; A0A0P0VPP5; Q0DXK6;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 110.
DE   RecName: Full=Transcription factor ILI5;
DE            Short=OsILI5;
DE   AltName: Full=Basic helix-loop-helix protein 170;
DE            Short=OsbHLH170;
DE   AltName: Full=Protein INCREASED LEAF INCLINATION 5;
DE   AltName: Full=Protein POSITIVE REGULATOR OF GRAIN LENGTH 2;
DE   AltName: Full=bHLH transcription factor bHLH170;
GN   Name=ILI5; Synonyms=BHLH170, PGL2;
GN   OrderedLocusNames=Os02g0747900, LOC_Os02g51320;
GN   ORFNames=OsJ_08379, OSJNBa0078N11.24;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=20472752; DOI=10.1104/pp.110.153593;
RA   Carretero-Paulet L., Galstyan A., Roig-Villanova I., Martinez-Garcia J.F.,
RA   Bilbao-Castro J.R., Robertson D.L.;
RT   "Genome-wide classification and evolutionary analysis of the bHLH family of
RT   transcription factors in Arabidopsis, poplar, rice, moss, and algae.";
RL   Plant Physiol. 153:1398-1412(2010).
RN   [6]
RP   FUNCTION, INTERACTION WITH APG, SUBCELLULAR LOCATION, AND TISSUE
RP   SPECIFICITY.
RX   PubMed=23136524; DOI=10.1270/jsbbs.62.133;
RA   Heang D., Sassa H.;
RT   "An atypical bHLH protein encoded by POSITIVE REGULATOR OF GRAIN LENGTH 2
RT   is involved in controlling grain length and weight of rice through
RT   interaction with a typical bHLH protein APG.";
RL   Breed. Sci. 62:133-141(2012).
CC   -!- FUNCTION: Atypical and probable non DNA-binding bHLH transcription
CC       factor that acts as a positive regulator of grain size. Binds the
CC       transcription repressor APG and forms a heterodimer of antagonistic
CC       basic helix-loop-helix transcription factors that regulates grain
CC       length and weight by controlling cell elongation in lemma and palea.
CC       {ECO:0000269|PubMed:23136524}.
CC   -!- SUBUNIT: Interacts with APG. {ECO:0000269|PubMed:23136524}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981,
CC       ECO:0000269|PubMed:23136524}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots, seedlings, young panicles,
CC       pistil, lemma and palea. Expressed at low levels in leaves.
CC       {ECO:0000269|PubMed:23136524}.
CC   -!- MISCELLANEOUS: Plants over-expressing ILI5 produce increased grain
CC       size, caused by elongated cells in lemma.
CC       {ECO:0000305|PubMed:23136524}.
CC   -!- SIMILARITY: Belongs to the bHLH protein family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF10032.2; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AP005848; BAD16450.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF10032.2; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014958; BAS80918.1; -; Genomic_DNA.
DR   EMBL; CM000139; EAZ24616.1; -; Genomic_DNA.
DR   RefSeq; XP_015624230.1; XM_015768744.1.
DR   AlphaFoldDB; Q6YUX0; -.
DR   SMR; Q6YUX0; -.
DR   STRING; 4530.OS02T0747900-00; -.
DR   PaxDb; Q6YUX0; -.
DR   PRIDE; Q6YUX0; -.
DR   EnsemblPlants; Os02t0747900-01; Os02t0747900-01; Os02g0747900.
DR   GeneID; 4330725; -.
DR   Gramene; Os02t0747900-01; Os02t0747900-01; Os02g0747900.
DR   KEGG; osa:4330725; -.
DR   eggNOG; ENOG502SURH; Eukaryota.
DR   HOGENOM; CLU_183267_0_0_1; -.
DR   InParanoid; Q6YUX0; -.
DR   OMA; EMMATMD; -.
DR   OrthoDB; 1589357at2759; -.
DR   Proteomes; UP000000763; Chromosome 2.
DR   Proteomes; UP000007752; Chromosome 2.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q6YUX0; OS.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0080113; P:regulation of seed growth; IMP:UniProtKB.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR044293; PRE.
DR   PANTHER; PTHR46446; PTHR46446; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   1: Evidence at protein level;
KW   Growth regulation; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..88
FT                   /note="Transcription factor ILI5"
FT                   /id="PRO_0000429096"
FT   DOMAIN          1..54
FT                   /note="bHLH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00981"
SQ   SEQUENCE   88 AA;  9905 MW;  DF0CEDA7C44184F9 CRC64;
     MSSRRSSRGS ISEEEINELI SKLQSLLPNS RRRGSSQAST TKLLKETCNY IKSLHREVDD
     LSDRLSDLMA TMDHNSPGAE IIRSILRS