ID   ILRUN_CHICK             Reviewed;         291 AA.
AC   Q5F3N9;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein ILRUN {ECO:0000305};
GN   Name=ILRUN; ORFNames=RCJMB04_11e11;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May have a roles as negative regulator of innate antiviral
CC       response. {ECO:0000250|UniProtKB:Q9H6K1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H6K1}. Nucleus
CC       {ECO:0000250|UniProtKB:Q9H6K1}.
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DR   EMBL; AJ851611; CAH65245.1; -; mRNA.
DR   RefSeq; NP_001026090.1; NM_001030919.1.
DR   AlphaFoldDB; Q5F3N9; -.
DR   SMR; Q5F3N9; -.
DR   STRING; 9031.ENSGALP00000004378; -.
DR   PaxDb; Q5F3N9; -.
DR   Ensembl; ENSGALT00000074053; ENSGALP00000055488; ENSGALG00000041792.
DR   GeneID; 419902; -.
DR   KEGG; gga:419902; -.
DR   CTD; 419902; -.
DR   VEuPathDB; HostDB:geneid_419902; -.
DR   eggNOG; KOG4351; Eukaryota.
DR   GeneTree; ENSGT00490000043415; -.
DR   HOGENOM; CLU_076188_1_0_1; -.
DR   InParanoid; Q5F3N9; -.
DR   OMA; FSAPCMS; -.
DR   OrthoDB; 1359706at2759; -.
DR   PhylomeDB; Q5F3N9; -.
DR   TreeFam; TF105872; -.
DR   PRO; PR:Q5F3N9; -.
DR   Proteomes; UP000000539; Chromosome 26.
DR   Bgee; ENSGALG00000041792; Expressed in testis and 12 other tissues.
DR   GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0016607; C:nuclear speck; IEA:Ensembl.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0016236; P:macroautophagy; IBA:GO_Central.
DR   GO; GO:0050687; P:negative regulation of defense response to virus; IEA:Ensembl.
DR   GO; GO:0043392; P:negative regulation of DNA binding; IEA:Ensembl.
DR   GO; GO:1900181; P:negative regulation of protein localization to nucleus; IEA:Ensembl.
DR   GO; GO:0032720; P:negative regulation of tumor necrosis factor production; IEA:Ensembl.
DR   GO; GO:0032480; P:negative regulation of type I interferon production; IEA:Ensembl.
DR   CDD; cd14947; NBR1_like; 1.
DR   CDD; cd14349; UBA_CF106; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR039517; C6orf106_UBA-like.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032350; N_BRCA1_central.
DR   InterPro; IPR009060; UBA-like_sf.
DR   Pfam; PF16158; N_BRCA1_IG; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Immunity; Innate immunity; Nucleus; Reference proteome.
FT   CHAIN           1..291
FT                   /note="Protein ILRUN"
FT                   /id="PRO_0000223320"
FT   REGION          199..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        199..221
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..275
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  31977 MW;  3C5E48510F25CCD0 CRC64;
     MEGMDVDLDA ELMQKFSCLG TTDKDVLIGE FQRLLGFQLS PAGCAFFLDM TNWNLQAAIG
     AYYDFESPNI NVPSMSFVED VTIGEGESIP PDTQFTKTWR IQNTGTEVWP PGVCLKYVGG
     DQFGHVNMVM VRSLEPQEIA DVSVQMCSPS TAGMYQGQWR MCTATGLYYG DVIWVILSVE
     VGGLLGVTQQ LSSFETEFNT QPHRKVEGNF NPFASPQKNR QPDENNLKDP GGSELGTISK
     NTWGPAPDQI EQDQNGLSQN SVNLSPSSHS NNLSVVTYSK GFHGPYPFGQ S