ID   ILRUN_DANRE             Reviewed;         283 AA.
AC   Q5BL31;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Protein ILRUN {ECO:0000305};
GN   Name=ilrun; ORFNames=zgc:101577;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May have a roles as negative regulator of innate antiviral
CC       response. {ECO:0000250|UniProtKB:Q9H6K1}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q9H6K1}. Nucleus
CC       {ECO:0000250|UniProtKB:Q9H6K1}.
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DR   EMBL; BC090819; AAH90819.1; -; mRNA.
DR   RefSeq; NP_001013560.1; NM_001013542.1.
DR   AlphaFoldDB; Q5BL31; -.
DR   SMR; Q5BL31; -.
DR   STRING; 7955.ENSDARP00000099995; -.
DR   PaxDb; Q5BL31; -.
DR   GeneID; 541415; -.
DR   KEGG; dre:541415; -.
DR   CTD; 64771; -.
DR   ZFIN; ZDB-GENE-050320-117; ilrun.
DR   eggNOG; KOG4351; Eukaryota.
DR   InParanoid; Q5BL31; -.
DR   PhylomeDB; Q5BL31; -.
DR   PRO; PR:Q5BL31; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:0043130; F:ubiquitin binding; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0016236; P:macroautophagy; IBA:GO_Central.
DR   CDD; cd14947; NBR1_like; 1.
DR   CDD; cd14349; UBA_CF106; 1.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR039517; C6orf106_UBA-like.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032350; N_BRCA1_central.
DR   InterPro; IPR009060; UBA-like_sf.
DR   Pfam; PF16158; N_BRCA1_IG; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Immunity; Innate immunity; Nucleus; Reference proteome.
FT   CHAIN           1..283
FT                   /note="Protein ILRUN"
FT                   /id="PRO_0000223321"
FT   REGION          198..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        198..219
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        240..254
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   283 AA;  31310 MW;  4AE47F713F5032BE CRC64;
     MEGMDIDLDQ ELMQKFSCMG TTDKDVLVSE FQRLLGFQLN PAGCAFFLDM TNWNLQAAIG
     AYYDFESPNI NTPSMSFVED VTIGEGESVP PDTPFTKTWR IQNTGTESWP PGVCLKYVGG
     DQFGHVNMVM VRSLDPQEIS DVSVQMRSPA VPGMYQGQWR MCTATGLFYG DVIWVILSVE
     EGGLLGVTQQ LSSFKTEFNT QPHRSLEGDY NPFASPQKNK QDTNEDHLKD PGGPWEAPLD
     SIQQDQNGLN HSSVNITPNG LQNNLSVVTY SQGINGPFPF GQS