ID   ILVB_KLEAE              Reviewed;          32 AA.
AC   Q09129;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Acetolactate synthase, catabolic;
DE            Short=ALS;
DE            EC=2.2.1.6;
DE   Flags: Fragment;
GN   Name=budB;
OS   Klebsiella aerogenes (Enterobacter aerogenes).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=548;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=VTT-E-87292;
RX   PubMed=8444801; DOI=10.1128/jb.175.5.1392-1404.1993;
RA   Blomqvist K., Nikkola M., Lehtovaara P., Suihko M.-L., Airaksinen U.,
RA   Straby K.B., Knowles J.K.C., Penttilae M.E.;
RT   "Characterization of the genes of the 2,3-butanediol operons from
RT   Klebsiella terrigena and Enterobacter aerogenes.";
RL   J. Bacteriol. 175:1392-1404(1993).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2;
CC         Xref=Rhea:RHEA:25249, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:58476; EC=2.2.1.6;
CC   -!- PATHWAY: Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-
CC       butane-2,3-diol from pyruvate: step 1/3.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- MISCELLANEOUS: Does not seem to require thiamine pyrophosphate.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TPP enzyme family. {ECO:0000305}.
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DR   EMBL; L04506; AAA56802.1; -; Genomic_DNA.
DR   PIR; B47069; B47069.
DR   AlphaFoldDB; Q09129; -.
DR   SMR; Q09129; -.
DR   UniPathway; UPA00626; UER00677.
DR   GO; GO:0003984; F:acetolactate synthase activity; IEA:UniProtKB-EC.
PE   3: Inferred from homology;
KW   Transferase.
FT   CHAIN           1..>32
FT                   /note="Acetolactate synthase, catabolic"
FT                   /id="PRO_0000090796"
FT   NON_TER         32
SQ   SEQUENCE   32 AA;  3530 MW;  0BA63C108E0878BB CRC64;
     MNSEKQSRQW AHGADMVVGQ LEAQGVKQVF GI