ID   APO3_ARATH              Reviewed;         402 AA.
AC   Q9FH50; Q94JX7;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=APO protein 3, mitochondrial;
DE   Flags: Precursor;
GN   Name=APO3; OrderedLocusNames=At5g61930; ORFNames=K22G18.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-402.
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
CC   -!- FUNCTION: May be involved in the stable assembly of several 4Fe-4S
CC       cluster-containing complexes of mitochondria. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC   -!- DOMAIN: The APO repeats may provide ligands for 4Fe-4S centers.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the APO family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00832}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK48980.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB022212; BAB08879.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97538.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED97539.1; -; Genomic_DNA.
DR   EMBL; AF370553; AAK48980.1; ALT_INIT; mRNA.
DR   EMBL; BT002086; AAN72097.1; -; mRNA.
DR   RefSeq; NP_001119475.1; NM_001126003.1.
DR   RefSeq; NP_568945.2; NM_125586.4.
DR   AlphaFoldDB; Q9FH50; -.
DR   PaxDb; Q9FH50; -.
DR   PRIDE; Q9FH50; -.
DR   EnsemblPlants; AT5G61930.1; AT5G61930.1; AT5G61930.
DR   EnsemblPlants; AT5G61930.2; AT5G61930.2; AT5G61930.
DR   GeneID; 836314; -.
DR   Gramene; AT5G61930.1; AT5G61930.1; AT5G61930.
DR   Gramene; AT5G61930.2; AT5G61930.2; AT5G61930.
DR   KEGG; ath:AT5G61930; -.
DR   Araport; AT5G61930; -.
DR   TAIR; locus:2156151; AT5G61930.
DR   eggNOG; ENOG502QRU6; Eukaryota.
DR   HOGENOM; CLU_033199_0_0_1; -.
DR   InParanoid; Q9FH50; -.
DR   OMA; YVWHVAD; -.
DR   OrthoDB; 720701at2759; -.
DR   PhylomeDB; Q9FH50; -.
DR   PRO; PR:Q9FH50; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FH50; baseline and differential.
DR   Genevisible; Q9FH50; AT.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   InterPro; IPR023342; APO_dom.
DR   Pfam; PF05634; APO_RNA-bind; 2.
DR   PROSITE; PS51499; APO; 2.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Repeat; Transit peptide.
FT   TRANSIT         1..13
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           14..402
FT                   /note="APO protein 3, mitochondrial"
FT                   /id="PRO_0000001932"
FT   DOMAIN          127..213
FT                   /note="APO 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00832"
FT   DOMAIN          294..380
FT                   /note="APO 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00832"
FT   REGION          37..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        41..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        2
FT                   /note="Q -> E (in Ref. 3; AAK48980)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   402 AA;  45912 MW;  42F8C6DC4D57F9F5 CRC64;
     MQRRKLVEIS IFVIRKSNFS SSIKSLTNLD VDVSVDNDED PLYADVPKPP KDKSERKPYP
     TPMKELIRRA KEEKQLRKLQ PCRVLEDPPD NGLLVPELVD VAHCVHRCRN MLLSGLSKII
     HHVPVHRCRL CAEVHIGKQG HEIRTCTGPG SGSRSATHVW KRGRVSDVVL FPKCFHLYDR
     AVKPRVIHDE RFTVPKISAV LELCIQAGVD LEKFPSKRRS KPVYSIEGRI VDFEDVNDGN
     SELAVTSTTT LIQEDDRCKE EKKSLKELSF ETMESWFEMV LGVRKLMERY RVWTCGYCPE
     IQVGPKGHKV RMCKATKHQM RDGMHAWQEA TIDDVVGPTY VWHVRDPTDG SVLDNSLKRF
     YGKAPAVIEM CVQGGAPVPD QYNSMMRLDV VYPQRDEVDL VA