ID   IMM1_ECOLX              Reviewed;         113 AA.
AC   P02985;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Colicin-E1 immunity protein;
DE   AltName: Full=ImmE1;
DE   AltName: Full=Microcin-E1 immunity protein;
GN   Name=imm;
OS   Escherichia coli.
OG   Plasmid ColE1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3936034; DOI=10.1073/pnas.82.24.8389;
RA   Waleh N.S., Johnson P.H.;
RT   "Structural and functional organization of the colicin E1 operon.";
RL   Proc. Natl. Acad. Sci. U.S.A. 82:8389-8393(1985).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=384144; DOI=10.1007/bf00268276;
RA   Oka A., Nomura N., Morita M., Sugisaki H., Sugimoto K., Takanami M.;
RT   "Nucleotide sequence of small ColE1 derivatives: structure of the regions
RT   essential for autonomous replication and colicin E1 immunity.";
RL   Mol. Gen. Genet. 172:151-159(1979).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8383110; DOI=10.1128/jb.175.5.1264-1271.1993;
RA   Jilk R.A., Makris J.C., Borchardt L., Reznikoff W.S.;
RT   "Implications of Tn5-associated adjacent deletions.";
RL   J. Bacteriol. 175:1264-1271(1993).
CC   -!- FUNCTION: This protein is able to protect a cell, which harbors the
CC       plasmid ColE1 encoding colicin E1, against colicin E1.
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DR   EMBL; J01566; AAB59122.1; -; Genomic_DNA.
DR   EMBL; M12543; AAA23066.1; -; Genomic_DNA.
DR   EMBL; V00268; CAA23529.1; -; Genomic_DNA.
DR   PIR; A94079; IMECE1.
DR   RefSeq; NP_040357.1; NC_001371.1.
DR   RefSeq; WP_000058760.1; NZ_WVVR01000058.1.
DR   RefSeq; YP_009069933.1; NC_025157.1.
DR   RefSeq; YP_009071083.1; NC_025178.1.
DR   AlphaFoldDB; P02985; -.
DR   GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR   GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
DR   InterPro; IPR003061; Microcin.
DR   Pfam; PF03526; Microcin; 1.
DR   PRINTS; PR01298; MICROCIN.
PE   4: Predicted;
KW   Bacteriocin immunity; Plasmid.
FT   CHAIN           1..113
FT                   /note="Colicin-E1 immunity protein"
FT                   /id="PRO_0000218700"
FT   CONFLICT        105
FT                   /note="G -> E (in Ref. 1; AAA23066)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   113 AA;  13287 MW;  FD32308B7C54E83E CRC64;
     MSLRYYIKNI LFGLYCTLIY IYLITKNSEG YYFLVSDKML YAIVISTILC PYSKYAIEYI
     AFNFIKKDFF ERRKNLNNAP VAKLNLFMLY NLLCLVLAIP FGLLGLFISI KNN