ID   IMMB_ECOLX              Reviewed;         175 AA.
AC   P22426;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Colicin-B immunity protein;
DE   AltName: Full=Microcin-B immunity protein;
GN   Name=cbi;
OS   Escherichia coli.
OG   Plasmid ColBM-pF166.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2830463; DOI=10.1007/bf00338410;
RA   Schramm E., Oelschlaeger T., Troeger W., Braun V.;
RT   "Sequence, expression and localization of the immunity protein for colicin
RT   B.";
RL   Mol. Gen. Genet. 211:176-182(1988).
CC   -!- FUNCTION: This protein is able to protect a cell, which harbors the
CC       plasmid ColB encoding colicin B, against colicin B.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
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DR   EMBL; M36645; AAA23540.1; -; Genomic_DNA.
DR   PIR; S06459; IMECB.
DR   RefSeq; WP_000203268.1; NZ_WVVE01000043.1.
DR   AlphaFoldDB; P22426; -.
DR   SMR; P22426; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR   GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
DR   InterPro; IPR005557; Colicin_im.
DR   Pfam; PF03857; Colicin_im; 1.
DR   PIRSF; PIRSF003003; Colicin_im; 1.
PE   4: Predicted;
KW   Bacteriocin immunity; Cell inner membrane; Cell membrane; Membrane;
KW   Plasmid; Transmembrane; Transmembrane helix.
FT   CHAIN           1..175
FT                   /note="Colicin-B immunity protein"
FT                   /id="PRO_0000218691"
FT   TRANSMEM        14..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   175 AA;  20186 MW;  402FBA57F1CDE5DD CRC64;
     MTSNKDKNKK ANEILYAFSI IGIIPLMAIL ILRINDPYSQ VLYYLYNKVA FLPSITSLHD
     PVMTTLMSNY NKTAPVMGIL VFLCTYKTRE IIKPVTRKLV VQSCFWGPVF YAILIYITLF
     YNLELTTAGG FFKLLSHNVI TLFILYCSIY FTVLTMTYAI LLMPLLVIKY FKGRQ