ID   IMMD_ECOLX              Reviewed;          87 AA.
AC   P11899; P71225;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Colicin-D immunity protein;
DE   AltName: Full=Microcin-D immunity protein;
GN   Name=cdi;
OS   Escherichia coli.
OG   Plasmid ColD-CA23.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2677603; DOI=10.1111/j.1365-2958.1989.tb00238.x;
RA   Roos U., Harkness R.E., Braun V.;
RT   "Assembly of colicin genes from a few DNA fragments. Nucleotide sequence of
RT   colicin D.";
RL   Mol. Microbiol. 3:891-902(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Pshennikova E.S., Kolot M.N., Khmel I.A.;
RT   "Structural and functional organization of the colicin operon of the ColD-
RT   CA23 plasmid.";
RL   Mol. Biol. (Mosk.) 21:1273-1278(1987).
CC   -!- FUNCTION: This protein is able to protect a cell, which harbors the
CC       plasmid ColD-CA23 encoding colicin D, against colicin D.
CC   -!- INTERACTION:
CC       P11899; P17998: cda; NbExp=3; IntAct=EBI-1038162, EBI-1038167;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA31485.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; X14941; CAA33073.1; -; Genomic_DNA.
DR   EMBL; X13086; CAA31485.1; ALT_INIT; Genomic_DNA.
DR   PIR; S09255; S09255.
DR   PDB; 1TFK; X-ray; 2.10 A; B=2-87.
DR   PDB; 1TFO; X-ray; 2.30 A; B=2-87.
DR   PDB; 1V74; X-ray; 2.00 A; B=1-87.
DR   PDBsum; 1TFK; -.
DR   PDBsum; 1TFO; -.
DR   PDBsum; 1V74; -.
DR   AlphaFoldDB; P11899; -.
DR   SMR; P11899; -.
DR   IntAct; P11899; 1.
DR   EvolutionaryTrace; P11899; -.
DR   GO; GO:0015643; F:toxic substance binding; IEA:InterPro.
DR   GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.650; -; 1.
DR   InterPro; IPR015287; Colicin_D_immunity_dom.
DR   InterPro; IPR036471; Colicin_D_sf.
DR   Pfam; PF09204; Colicin_immun; 1.
DR   SUPFAM; SSF101125; SSF101125; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Bacteriocin immunity; Plasmid.
FT   CHAIN           1..87
FT                   /note="Colicin-D immunity protein"
FT                   /id="PRO_0000218696"
FT   CONFLICT        20
FT                   /note="A -> V (in Ref. 2; CAA31485)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        52
FT                   /note="F -> S (in Ref. 2; CAA31485)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        85..87
FT                   /note="FKL -> LKS (in Ref. 2; CAA31485)"
FT                   /evidence="ECO:0000305"
FT   HELIX           5..14
FT                   /evidence="ECO:0007829|PDB:1V74"
FT   HELIX           20..34
FT                   /evidence="ECO:0007829|PDB:1V74"
FT   HELIX           42..56
FT                   /evidence="ECO:0007829|PDB:1V74"
FT   HELIX           71..84
FT                   /evidence="ECO:0007829|PDB:1V74"
SQ   SEQUENCE   87 AA;  10058 MW;  B558A5E3B44990F2 CRC64;
     MNKMAMIDLA KLFLASKITA IEFSERICVE RRRLYGVKDL SPNILNCGEE LFMAAERFEP
     DADRANYEID DNGLKVEVRS ILEKFKL