ID   IMP1L_XENTR             Reviewed;         167 AA.
AC   Q28I39;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Mitochondrial inner membrane protease subunit 1;
DE            EC=3.4.21.-;
DE   AltName: Full=IMP1-like protein;
GN   Name=immp1l; ORFNames=TEgg068a14.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the removal of transit peptides required for the
CC       targeting of proteins from the mitochondrial matrix, across the inner
CC       membrane, into the inter-membrane space. {ECO:0000250}.
CC   -!- SUBUNIT: Heterodimer of 2 subunits, IMMPL1 and IMMPL2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the peptidase S26 family. IMP1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; CR760609; CAJ81736.1; -; mRNA.
DR   RefSeq; NP_001016589.1; NM_001016589.2.
DR   AlphaFoldDB; Q28I39; -.
DR   SMR; Q28I39; -.
DR   STRING; 8364.ENSXETP00000017934; -.
DR   PaxDb; Q28I39; -.
DR   Ensembl; ENSXETT00000017934; ENSXETP00000017934; ENSXETG00000008178.
DR   GeneID; 549343; -.
DR   KEGG; xtr:549343; -.
DR   CTD; 196294; -.
DR   Xenbase; XB-GENE-5806212; immp1l.
DR   eggNOG; KOG0171; Eukaryota.
DR   HOGENOM; CLU_028723_4_3_1; -.
DR   InParanoid; Q28I39; -.
DR   OMA; STHWFWE; -.
DR   OrthoDB; 1211147at2759; -.
DR   PhylomeDB; Q28I39; -.
DR   TreeFam; TF315083; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000008178; Expressed in egg cell and 14 other tissues.
DR   ExpressionAtlas; Q28I39; baseline and differential.
DR   GO; GO:0042720; C:mitochondrial inner membrane peptidase complex; IBA:GO_Central.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006627; P:protein processing involved in protein targeting to mitochondrion; IBA:GO_Central.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   CDD; cd06530; S26_SPase_I; 1.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR000223; Pept_S26A_signal_pept_1.
DR   InterPro; IPR019533; Peptidase_S26.
DR   Pfam; PF10502; Peptidase_S26; 2.
DR   PRINTS; PR00727; LEADERPTASE.
DR   SUPFAM; SSF51306; SSF51306; 1.
DR   TIGRFAMs; TIGR02227; sigpep_I_bact; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Membrane; Mitochondrion; Mitochondrion inner membrane; Protease;
KW   Reference proteome.
FT   CHAIN           1..167
FT                   /note="Mitochondrial inner membrane protease subunit 1"
FT                   /id="PRO_0000259575"
FT   ACT_SITE        40
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        83
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   167 AA;  18661 MW;  241987D86D3E1E7F CRC64;
     MIRRIVGKTL GLLGYTIQYG CIAHCAFEYI GEVVICSGPS MEPTIRNYDV LLCDNLSRHF
     FSIHKGDIIV AKSPDKPSVN ICKRVIGLEG DKVCMSSPSA LLKRHTYVPK GHVWLEGDNL
     DNSTDSRSYG PVPYALIRGR ICLRVWPLES FGPLKESPNG RIQDNWP