IMP4_ASHGO
ID IMP4_ASHGO Reviewed; 283 AA.
AC Q755T8;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2013, sequence version 2.
DT 25-MAY-2022, entry version 94.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4;
DE Short=U3 snoRNP protein IMP4;
GN Name=IMP4; OrderedLocusNames=AER430W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 209.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the U3 small nucleolar ribonucleoprotein.
CC Required for the early cleavages at sites A0, A1 and A2 during 18S
CC ribosomal pre-RNA processing (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of a heterotrimeric complex containing IMP3, IMP4
CC and MPP10. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR EMBL; AE016818; AAS53109.2; -; Genomic_DNA.
DR RefSeq; NP_985285.2; NM_210639.2.
DR AlphaFoldDB; Q755T8; -.
DR SMR; Q755T8; -.
DR STRING; 33169.AAS53109; -.
DR EnsemblFungi; AAS53109; AAS53109; AGOS_AER430W.
DR GeneID; 4621504; -.
DR KEGG; ago:AGOS_AER430W; -.
DR eggNOG; KOG2781; Eukaryota.
DR HOGENOM; CLU_040063_2_0_1; -.
DR InParanoid; Q755T8; -.
DR OMA; IGTMSEQ; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0034457; C:Mpp10 complex; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0042134; F:rRNA primary transcript binding; IEA:EnsemblFungi.
DR GO; GO:0043047; F:single-stranded telomeric DNA binding; IEA:EnsemblFungi.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0042274; P:ribosomal small subunit biogenesis; IEA:EnsemblFungi.
DR GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR InterPro; IPR007109; Brix.
DR InterPro; IPR044281; IMP4/RPF1.
DR PANTHER; PTHR22734; PTHR22734; 1.
DR Pfam; PF04427; Brix; 1.
DR SMART; SM00879; Brix; 1.
DR PROSITE; PS50833; BRIX; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..283
FT /note="U3 small nucleolar ribonucleoprotein protein IMP4"
FT /id="PRO_0000120240"
FT DOMAIN 79..260
FT /note="Brix"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ SEQUENCE 283 AA; 32545 MW; CA92BBD4696369FF CRC64;
MLRRQARERR EYLYRKAQEL QESQLQQKRD LIKQALAQGK PLPKEVADDT KLQRDYQYDE
SAQESIDDEY SALSGIVDPK VIVTTSRDPS TRLSQFAKEV KLLFPTSVRL NRGNYIMKNL
VDACQKSGTT DLVVLHEHRG VPTALTISHF PHGPTASFSL HNVVLRHDIL NAGNQSEVHP
HLIFDNFTTP LGQRVVKILK HMFPPGVKKD SPRVITFANR GDFISVRQHV YVKTRDGVEL
AEVGPRFEMK LYELTLGTLE NKDADVEWQL RRFVRTANRK DYL
