ID   IMP4_BOVIN              Reviewed;         291 AA.
AC   Q0VD01;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4;
DE            Short=U3 snoRNP protein IMP4;
GN   Name=IMP4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal skin;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein
CC       (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal
CC       RNA processing (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of a heterotrimeric complex containing IMP3, IMP4
CC       and MPHOSPH10. Interacts with MPHOSPH10 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; BC119909; AAI19910.1; -; mRNA.
DR   RefSeq; NP_001069085.1; NM_001075617.1.
DR   RefSeq; XP_010800080.1; XM_010801778.2.
DR   AlphaFoldDB; Q0VD01; -.
DR   SMR; Q0VD01; -.
DR   STRING; 9913.ENSBTAP00000004184; -.
DR   PaxDb; Q0VD01; -.
DR   PRIDE; Q0VD01; -.
DR   Ensembl; ENSBTAT00000004184; ENSBTAP00000004184; ENSBTAG00000003225.
DR   GeneID; 513405; -.
DR   KEGG; bta:513405; -.
DR   CTD; 92856; -.
DR   VEuPathDB; HostDB:ENSBTAG00000003225; -.
DR   VGNC; VGNC:30183; IMP4.
DR   eggNOG; KOG2781; Eukaryota.
DR   GeneTree; ENSGT00940000153231; -.
DR   HOGENOM; CLU_040063_2_0_1; -.
DR   InParanoid; Q0VD01; -.
DR   OMA; IGTMSEQ; -.
DR   OrthoDB; 768872at2759; -.
DR   TreeFam; TF300016; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000003225; Expressed in metanephros cortex and 105 other tissues.
DR   GO; GO:0001650; C:fibrillar center; IEA:Ensembl.
DR   GO; GO:0034457; C:Mpp10 complex; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IEA:InterPro.
DR   GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR044281; IMP4/RPF1.
DR   PANTHER; PTHR22734; PTHR22734; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..291
FT                   /note="U3 small nucleolar ribonucleoprotein protein IMP4"
FT                   /id="PRO_0000269725"
FT   DOMAIN          83..264
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ   SEQUENCE   291 AA;  33681 MW;  0179E37B425A8976 CRC64;
     MLRREARLRR EYLYRKAREE AERTAQERKD KVRRALEENR LIPTELRREA LALQGSLEFD
     DAGGEGVTNH VDDEYRWAGV EDPKVMITTS RDPSSRLKMF AKELKLVFPG AQRMNRGRHE
     VGALVRACKA NGVTDLLVVH EHRGTPVGLI VSHLPFGPTA YFTLCNVVMR HDIPDLGTAS
     EAKPHLIMHG FSSRLGKRVS DILRYLFPVP KDDSRRVITF ANQDDYISFR HHVYKKTNHR
     NVELTEVGPR FELKLYMIRL GTLEQEATAD VEWRWHPYTN TAHKRVFLSA E