IMP4_DEBHA
ID IMP4_DEBHA Reviewed; 284 AA.
AC Q6BYD9;
DT 16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 16-DEC-2008, sequence version 2.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4;
DE Short=U3 snoRNP protein IMP4;
GN Name=IMP4; OrderedLocusNames=DEHA2A10318g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Component of the U3 small nucleolar ribonucleoprotein.
CC Required for the early cleavages at sites A0, A1 and A2 during 18S
CC ribosomal pre-RNA processing (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Component of a heterotrimeric complex containing IMP3, IMP4
CC and MPP10. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR EMBL; CR382133; CAG84746.2; -; Genomic_DNA.
DR RefSeq; XP_456780.2; XM_456780.1.
DR AlphaFoldDB; Q6BYD9; -.
DR SMR; Q6BYD9; -.
DR STRING; 4959.XP_456780.2; -.
DR EnsemblFungi; CAG84746; CAG84746; DEHA2A10318g.
DR GeneID; 2899606; -.
DR KEGG; dha:DEHA2A10318g; -.
DR VEuPathDB; FungiDB:DEHA2A10318g; -.
DR eggNOG; KOG2781; Eukaryota.
DR HOGENOM; CLU_040063_2_0_1; -.
DR InParanoid; Q6BYD9; -.
DR OMA; IGTMSEQ; -.
DR OrthoDB; 768872at2759; -.
DR Proteomes; UP000000599; Chromosome A.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0042134; F:rRNA primary transcript binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR007109; Brix.
DR InterPro; IPR044281; IMP4/RPF1.
DR PANTHER; PTHR22734; PTHR22734; 1.
DR Pfam; PF04427; Brix; 1.
DR SMART; SM00879; Brix; 1.
DR PROSITE; PS50833; BRIX; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..284
FT /note="U3 small nucleolar ribonucleoprotein protein IMP4"
FT /id="PRO_0000120242"
FT DOMAIN 79..260
FT /note="Brix"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ SEQUENCE 284 AA; 33011 MW; 2B0B3331AC1B88EE CRC64;
MIRKQARERR EYLYRKSLEL QESSLTEKRQ QLKAALASGK PLSKELAEDK ELQKDFIYDE
SEQTEIDDEY SALSGISEPK VLITTSRNPS VKLLQFSKEI KLMFPNSIKL NRGNYVITDL
VATCQRVQIS DLIILHEHRG IPTSLTISHF PHGPSIIFTL HNVKLRHDLP EIGNSSESYP
HLVFENFTSE LGKRVVKIMK HLFPPGVKKD SSRVITFINN DDFISVRHHM YVKTKDTVEL
SEVGPRFEMR LYELRLGLLD NKDSEVEWQL RRFIRTGNRK NYLG