ID   IMP4_PONAB              Reviewed;         291 AA.
AC   Q5R947;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2005, sequence version 2.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=U3 small nucleolar ribonucleoprotein protein IMP4;
DE            Short=U3 snoRNP protein IMP4;
GN   Name=IMP4;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-291.
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the 60-80S U3 small nucleolar ribonucleoprotein
CC       (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal
CC       RNA processing (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of a heterotrimeric complex containing IMP3, IMP4
CC       and MPHOSPH10. Interacts with MPHOSPH10 (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; CR859548; CAH91713.1; -; mRNA.
DR   RefSeq; XP_009233960.1; XM_009235685.1.
DR   AlphaFoldDB; Q5R947; -.
DR   SMR; Q5R947; -.
DR   STRING; 9601.ENSPPYP00000014966; -.
DR   GeneID; 100174526; -.
DR   KEGG; pon:100174526; -.
DR   CTD; 92856; -.
DR   eggNOG; KOG2781; Eukaryota.
DR   HOGENOM; CLU_040063_2_0_1; -.
DR   InParanoid; Q5R947; -.
DR   OMA; IGTMSEQ; -.
DR   OrthoDB; 768872at2759; -.
DR   TreeFam; TF300016; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042134; F:rRNA primary transcript binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR007109; Brix.
DR   InterPro; IPR044281; IMP4/RPF1.
DR   PANTHER; PTHR22734; PTHR22734; 1.
DR   Pfam; PF04427; Brix; 1.
DR   SMART; SM00879; Brix; 1.
DR   PROSITE; PS50833; BRIX; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..291
FT                   /note="U3 small nucleolar ribonucleoprotein protein IMP4"
FT                   /id="PRO_0000120238"
FT   DOMAIN          83..264
FT                   /note="Brix"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00034"
SQ   SEQUENCE   291 AA;  33727 MW;  461675DFFE70C580 CRC64;
     MLRREARLRR EYLYRKAREE AQRSAQERKE RLRRALEENR LIPTELRREA LALQGSLEFD
     DAGGEGVTSH VDDEYRWAGV EDPKVMITTS RDPSSRLKMF AKELKLVFPG AQRMNRGRHE
     VGALVRACKA NGVTDLLVVH EHRGTPVGLI VSHLPFGPTA YFTLCNVVMR HDIPDLGTMS
     EAKPHLITHG FSSRLGKRVS DILRYLFPVP KDDSHRVITF ANQDDYISFR HHVYKKTDHR
     NVELTEVGPR FELKLYMIRL GTLEQEATAD VEWRWHPYTN TARKRVFLSA E