ID   4HBT_ARTGO              Reviewed;         151 AA.
AC   Q7BI34;
DT   02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=4-hydroxybenzoyl-CoA thioesterase {ECO:0000250|UniProtKB:Q04416};
DE            Short=4-HBA-CoA thioesterase {ECO:0000250|UniProtKB:Q04416};
DE            EC=3.1.2.23;
GN   Name=fcbC {ECO:0000312|EMBL:AAG42237.1};
OS   Arthrobacter globiformis.
OG   Plasmid pCA311 {ECO:0000312|EMBL:AAG42237.1}.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=1665;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAG42237.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=KZT1 {ECO:0000312|EMBL:AAG42237.1};
RA   Rodrigues J.L.M., Rech S., Tsoi T.V., Kachel C.A., Cole J.R., Tiedje J.M.;
RT   "Sequence analysis, expression, and regulation of the 4-chlorobenzoate
RT   degradation (fcb) operon from Arthrobacter globiformis strain KZT1.";
RL   Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=4-hydroxybenzoyl-CoA + H2O = 4-hydroxybenzoate + CoA + H(+);
CC         Xref=Rhea:RHEA:11948, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:17879, ChEBI:CHEBI:57287, ChEBI:CHEBI:57356; EC=3.1.2.23;
CC         Evidence={ECO:0000250|UniProtKB:Q04416};
CC   -!- PATHWAY: Xenobiotic degradation; 4-chlorobenzoate degradation; 4-
CC       hydroxybenzoate from 4-chlorobenzoate: step 3/3.
CC   -!- SUBUNIT: Homotetramer. {ECO:0000250|UniProtKB:Q04416}.
CC   -!- SIMILARITY: Belongs to the thioesterase PaaI family. {ECO:0000305}.
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DR   EMBL; AF304300; AAG42237.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q7BI34; -.
DR   SMR; Q7BI34; -.
DR   UniPathway; UPA01011; UER01022.
DR   GO; GO:0018739; F:4-hydroxybenzoyl-CoA thioesterase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR003736; PAAI_dom.
DR   InterPro; IPR006683; Thioestr_dom.
DR   Pfam; PF03061; 4HBT; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
DR   TIGRFAMs; TIGR00369; unchar_dom_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Plasmid.
FT   CHAIN           1..151
FT                   /note="4-hydroxybenzoyl-CoA thioesterase"
FT                   /id="PRO_0000400828"
FT   ACT_SITE        73
FT                   /evidence="ECO:0000250|UniProtKB:Q04416"
FT   BINDING         100..102
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   151 AA;  16394 MW;  95738A4BBD241A7E CRC64;
     MHRTSNGSHA TGGNLPDVAS HYPVAYEQTL DGTVGFVIDE MTPERATASV EVTDTLRQRW
     GLVHGGAYCA LAEMLATEAT VAVVHEKGMM AVGQSNHTSF FRPVKEGHVR AEAVRIHAGS
     TTWFWDVSLR DDAGRLCAVS SMSIAVRPRR D