IMUA_CAUVN
ID IMUA_CAUVN Reviewed; 244 AA.
AC B8H429;
DT 16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 2.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Protein ImuA;
GN Name=imuA; OrderedLocusNames=CCNA_03319;
OS Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=565050;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA1000 / CB15N;
RX PubMed=20472802; DOI=10.1128/jb.00255-10;
RA Marks M.E., Castro-Rojas C.M., Teiling C., Du L., Kapatral V.,
RA Walunas T.L., Crosson S.;
RT "The genetic basis of laboratory adaptation in Caulobacter crescentus.";
RL J. Bacteriol. 192:3678-3688(2010).
RN [2]
RP FUNCTION.
RX PubMed=15886391; DOI=10.1093/nar/gki551;
RA Galhardo R.S., Rocha R.P., Marques M.V., Menck C.F.M.;
RT "An SOS-regulated operon involved in damage-inducible mutagenesis in
RT Caulobacter crescentus.";
RL Nucleic Acids Res. 33:2603-2614(2005).
CC -!- FUNCTION: Along with DnaE2 and ImuB is required for the error-prone
CC processing of DNA lesions. {ECO:0000269|PubMed:15886391}.
CC -!- INDUCTION: Up-regulated in response to DNA damage in a RecA-dependent
CC manner.
CC -!- SEQUENCE CAUTION:
CC Sequence=ACL96783.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP001340; ACL96783.1; ALT_INIT; Genomic_DNA.
DR RefSeq; YP_002518691.1; NC_011916.1.
DR AlphaFoldDB; B8H429; -.
DR SMR; B8H429; -.
DR EnsemblBacteria; ACL96783; ACL96783; CCNA_03319.
DR GeneID; 7330343; -.
DR KEGG; ccs:CCNA_03319; -.
DR PATRIC; fig|565050.3.peg.3236; -.
DR HOGENOM; CLU_065750_1_0_5; -.
DR OMA; IVWCLTR; -.
DR OrthoDB; 1941503at2; -.
DR PhylomeDB; B8H429; -.
DR Proteomes; UP000001364; Chromosome.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR017026; ImuA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PIRSF; PIRSF034285; UCP034285; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 2: Evidence at transcript level;
KW DNA damage; DNA repair; Reference proteome.
FT CHAIN 1..244
FT /note="Protein ImuA"
FT /id="PRO_0000378298"
SQ SEQUENCE 244 AA; 25453 MW; 445B8ABD3CAD4AC6 CRC64;
MEAGTRTPTP VLSFGEPSID GCFPGGGLPL GGWHEVTGAG LEDETGAAPA AFVTQLIRGL
TDRKGGAVVW VARRADLFAP GLLGLGFPAA RLIQVRARDE AETLSLLEDA LSTQGVAAAV
AEAEAPDLTA GRRLQLACEK RGGFGVVLHR RPYGGRAGGK PRLVSGSASF SRWRIAPAPS
GPPPDDIGLG PPRWRVELER CRGGRPGGWI LQAQEAGHGP HPFRLVSQLA DHDVAAAEAG
RRFG