ID   IN80D_DICDI             Reviewed;         675 AA.
AC   Q54J07;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=INO80 complex subunit D;
GN   ORFNames=DDB_G0288447;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Putative regulatory component of the chromatin remodeling
CC       INO80 complex which is involved in transcriptional regulation, DNA
CC       replication and probably DNA repair. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the chromatin-remodeling INO80 complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the INO80D family. {ECO:0000305}.
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DR   EMBL; AAFI02000111; EAL63249.1; -; Genomic_DNA.
DR   RefSeq; XP_636723.1; XM_631631.1.
DR   AlphaFoldDB; Q54J07; -.
DR   SMR; Q54J07; -.
DR   STRING; 44689.DDB0215968; -.
DR   PaxDb; Q54J07; -.
DR   PRIDE; Q54J07; -.
DR   EnsemblProtists; EAL63249; EAL63249; DDB_G0288447.
DR   GeneID; 8626600; -.
DR   KEGG; ddi:DDB_G0288447; -.
DR   dictyBase; DDB_G0288447; -.
DR   eggNOG; ENOG502QTMA; Eukaryota.
DR   HOGENOM; CLU_407377_0_0_1; -.
DR   InParanoid; Q54J07; -.
DR   OMA; CSKRPME; -.
DR   PRO; PR:Q54J07; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   InterPro; IPR025927; Potential_DNA-bd.
DR   Pfam; PF13891; zf-C3Hc3H; 2.
PE   3: Inferred from homology;
KW   DNA damage; DNA recombination; DNA repair; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..675
FT                   /note="INO80 complex subunit D"
FT                   /id="PRO_0000343654"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          183..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          274..324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          473..523
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          627..675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        283..324
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        473..519
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   675 AA;  78233 MW;  F2A24B10A7BD213E CRC64;
     MNNNSNNNNN NNIDQKNETT NEITNNTSNN NNIINNVNQN STSITTSPIL SPNNNINDNS
     MMDGKRLCAS SKKVCSKRPM ETYRFCIKHI LEEPSAPFKQ CEFISLKSQK QCTNPVSIKE
     KDPRFCVSHK HIIESTKKRV LESVVSSITS PSSSSPLPNA SLIGSNSNIT SPLQNLTTLN
     AFTGNNNNNT TTTTTTTTTN STPSLNFDQQ INIDIDNING GDEPNLSLSA SSFNFNIISN
     NDEEPKKKIM KILDRHGISQ GRFYQDFKQN LKQLKQKHKQ KQQLQNQKMF EQSQQQDQQQ
     KPVQQPIQQQ QQQDQLQIQE ERQVSQQDEI LEKQQQQQQQ QQQQQQQQQQ QQQQQQQQKK
     QQQELQIENN KENENINESN YFGEEFIEKD LEIELFKAMD DGHLSELCED FDSDFYFASS
     SVLTDEELIQ RRKIYISKLI LLYKKQYNRF KERLRIIRRH YISTSLSLNQ QNDSNKMEID
     NNNDNNINNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNK LNKRKEEGNL CLSVNCKVKP
     MLLSKYCYSH ILQDKDQKLF HECTYQLSAN KKCGYPILKV QIPTLCREHL DIYETNNEII
     KSLPKKQKQF IKQRIDIEKH NAPSTLVPVT QPINQNNQNN NNNNTNNSSK EESKDNNNNN
     NNKEILKDSD NTMIS