INA17_ASHGO
ID INA17_ASHGO Reviewed; 159 AA.
AC Q75D33;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Inner membrane assembly complex subunit 17 {ECO:0000250|UniProtKB:Q02888};
DE Flags: Precursor;
GN Name=INA17 {ECO:0000250|UniProtKB:Q02888}; OrderedLocusNames=ABR190C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the INA complex (INAC) that promotes the
CC biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the
CC assembly of the peripheral stalk and promotes the assembly of the
CC catalytic F(1)-domain with the membrane-embedded F(0)-domain.
CC {ECO:0000250|UniProtKB:Q02888}.
CC -!- SUBUNIT: Component of the inner membrane assembly (INA) complex,
CC composed of INA17 and INA22. Interacts with a subset of F(1)F(0)-ATP
CC synthase subunits of the F(1)-domain and the peripheral stalk.
CC {ECO:0000250|UniProtKB:Q02888}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:Q02888}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the INA17 family. {ECO:0000305}.
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DR EMBL; AE016815; AAS50962.2; -; Genomic_DNA.
DR RefSeq; NP_983138.2; NM_208491.2.
DR AlphaFoldDB; Q75D33; -.
DR SMR; Q75D33; -.
DR STRING; 33169.AAS50962; -.
DR EnsemblFungi; AAS50962; AAS50962; AGOS_ABR190C.
DR GeneID; 4619248; -.
DR KEGG; ago:AGOS_ABR190C; -.
DR eggNOG; ENOG502S3U1; Eukaryota.
DR HOGENOM; CLU_127263_0_0_1; -.
DR InParanoid; Q75D33; -.
DR OMA; HYVWWKL; -.
DR Proteomes; UP000000591; Chromosome II.
DR GO; GO:1990524; C:INA complex; IEA:EnsemblFungi.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:1990677; C:mitochondrial inner membrane assembly complex; IEA:EnsemblFungi.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; IEA:EnsemblFungi.
PE 3: Inferred from homology;
KW Chaperone; Coiled coil; Membrane; Mitochondrion;
KW Mitochondrion inner membrane; Reference proteome; Transit peptide;
KW Transmembrane; Transmembrane helix.
FT TRANSIT 1..18
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 19..159
FT /note="Inner membrane assembly complex subunit 17"
FT /id="PRO_0000399877"
FT TOPO_DOM 19..77
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000250|UniProtKB:Q02888"
FT TRANSMEM 78..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..159
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000250|UniProtKB:Q02888"
FT COILED 102..124
FT /evidence="ECO:0000255"
SQ SEQUENCE 159 AA; 18373 MW; E7229FD0A7095E72 CRC64;
MIRYALLRSG RRTLQTRPSP QTLEELARLK SLEDVDSSVI RKLINQRTEE VNAQNEAQML
KKLSAEGRDL QNVPGSRYAR PLWLLLIGCA SVYLVRDWLR MKAEYDARET TLETRVEGLE
AELKYLLEPK PGVLEVEVVQ TEVASSAPWY KRWLWSGSR
