INA17_SCHPO
ID INA17_SCHPO Reviewed; 112 AA.
AC P0CU26;
DT 05-OCT-2016, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 1.
DT 25-MAY-2022, entry version 9.
DE RecName: Full=Inner membrane assembly complex subunit 17 {ECO:0000250|UniProtKB:Q02888};
DE Flags: Precursor;
GN Name=ina17 {ECO:0000250|UniProtKB:Q02888};
GN ORFNames=SPBC3B8.10 {ECO:0000312|PomBase:SPBC3B8.10};
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP IDENTIFICATION.
RX PubMed=26494834; DOI=10.1093/dnares/dsv025;
RA Jimenez J., Duncan C.D., Gallardo M., Mata J., Perez-Pulido A.J.;
RT "AnABlast: a new in silico strategy for the genome-wide search of novel
RT genes and fossil regions.";
RL DNA Res. 22:439-449(2015).
CC -!- FUNCTION: Component of the INA complex (INAC) that promotes the
CC biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the
CC assembly of the peripheral stalk and promotes the assembly of the
CC catalytic F(1)-domain with the membrane-embedded F(0)-domain.
CC {ECO:0000250|UniProtKB:Q02888}.
CC -!- SUBUNIT: Component of the inner membrane assembly (INA) complex.
CC Interacts with a subset of F(1)F(0)-ATP synthase subunits of the F(1)-
CC domain and the peripheral stalk. {ECO:0000250|UniProtKB:Q02888}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane
CC {ECO:0000250|UniProtKB:Q02888}; Single-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the INA17 family. {ECO:0000305}.
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DR EMBL; CU329671; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; P0CU26; -.
DR SMR; P0CU26; -.
DR PomBase; SPBC3B8.10; ina17.
DR VEuPathDB; FungiDB:SPBC3B8.10; -.
DR PRO; PR:P0CU26; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:1990524; C:INA complex; ISO:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0033615; P:mitochondrial proton-transporting ATP synthase complex assembly; ISO:PomBase.
PE 3: Inferred from homology;
KW Chaperone; Membrane; Mitochondrion; Mitochondrion inner membrane;
KW Reference proteome; Transit peptide; Transmembrane; Transmembrane helix.
FT TRANSIT 1..24
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 25..112
FT /note="Inner membrane assembly complex subunit 17"
FT /evidence="ECO:0000255"
FT /id="PRO_0000437260"
FT TOPO_DOM 25..44
FT /note="Mitochondrial matrix"
FT /evidence="ECO:0000305"
FT TRANSMEM 45..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 63..112
FT /note="Mitochondrial intermembrane"
FT /evidence="ECO:0000305"
SQ SEQUENCE 112 AA; 13379 MW; 372E0BD3AB7999D3 CRC64;
MLRKLPINFA KWTVKKVPVQ QKRFNSQQKE ISPHIMFYKN YARPLGKVTL FALATYYGLE
IVWWKLDASE QEAIKNSKLL ICESSFSLLT FRRITEFREC EIKTRDLYDP EI
