INCC2_ECOLX
ID INCC2_ECOLX Reviewed; 364 AA.
AC P07673;
DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1988, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Protein IncC;
GN Name=incC;
OS Escherichia coli.
OG Plasmid IncP-alpha RK2.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=562;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3520485; DOI=10.1093/nar/14.11.4453;
RA Thomas C.M., Smith C.A.;
RT "The trfB region of broad host range plasmid RK2: the nucleotide sequence
RT reveals incC and key regulatory gene trfB/korA/korD as overlapping genes.";
RL Nucleic Acids Res. 14:4453-4469(1986).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 330-364.
RX PubMed=3309894; DOI=10.1093/nar/15.18.7443;
RA Theophilus B.D.B., Thomas C.M.;
RT "Nucleotide sequence of the transcriptional repressor gene korB which plays
RT a key role in regulation of the copy number of broad host range plasmid
RT RK2.";
RL Nucleic Acids Res. 15:7443-7450(1987).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 342-364.
RX PubMed=3430606; DOI=10.1016/0022-2836(87)90307-x;
RA Kornacki J.A., Balderes P.J., Figurski D.H.;
RT "Nucleotide sequence of korB, a replication control gene of broad host-
RT range plasmid RK2.";
RL J. Mol. Biol. 198:211-222(1987).
CC -!- FUNCTION: This is one of the proteins encoded by the trfB operon; it is
CC involved in plasmid maintenance and replication.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative initiation; Named isoforms=2;
CC Name=Long;
CC IsoId=P07673-1; Sequence=Displayed;
CC Name=Short; Synonyms=Small;
CC IsoId=P07673-2; Sequence=VSP_018860;
CC -!- SIMILARITY: Belongs to the ParA family. {ECO:0000305}.
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DR EMBL; X03962; CAA27595.1; -; Genomic_DNA.
DR EMBL; Y00448; CAA68502.1; -; Genomic_DNA.
DR EMBL; X06543; CAA29789.1; -; Genomic_DNA.
DR AlphaFoldDB; P07673; -.
DR BMRB; P07673; -.
DR SMR; P07673; -.
DR DIP; DIP-17008N; -.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF13614; AAA_31; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 3: Inferred from homology;
KW Alternative initiation; DNA replication; Plasmid.
FT CHAIN 1..364
FT /note="Protein IncC"
FT /id="PRO_0000024483"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..105
FT /note="Missing (in isoform Short)"
FT /evidence="ECO:0000305"
FT /id="VSP_018860"
SQ SEQUENCE 364 AA; 38134 MW; 36241B743C53E0BE CRC64;
MGVIHEETAY RKPVPGGDPG AGSGAADHRD SAGRLSRWEA TGDVRNVAGT DQGRSVASGA
SRVGRVRGQE LARGVRAGNG GSAGTSGVHR PEVGSGRQEK TGNQTMKTLV TANQKGGVGK
TSTLVHLAFD FFERGLRVAV IDLDPQGNAS YTLKDFATGL HASKLFGAVP AGGWTETAPA
AGDGQAARLA LIESNPVLAN AERLSLDDAR ELFGANIKAL ANQGFDVCLI DTAPTLGVGL
AAALFAADYV LSPIELEAYS IQGIKKMVTT IANVRQKNAK LQFLGMVPSK VDARNPRHAR
HQAELLAAYP KMMIPATVGL RSSIADALAS GVPVWKIKKT AARKASKEVR ALADYVFTKM
EISQ