INCD_CHLTR
ID INCD_CHLTR Reviewed; 141 AA.
AC P0DJI3; O84117; Q9RPQ1;
DT 13-JUN-2012, integrated into UniProtKB/Swiss-Prot.
DT 13-JUN-2012, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Inclusion membrane protein D;
GN Name=incD; OrderedLocusNames=CT_115;
OS Chlamydia trachomatis (strain D/UW-3/Cx).
OC Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae;
OC Chlamydia/Chlamydophila group; Chlamydia.
OX NCBI_TaxID=272561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D/UW-3/Cx;
RX PubMed=9784136; DOI=10.1126/science.282.5389.754;
RA Stephens R.S., Kalman S., Lammel C.J., Fan J., Marathe R., Aravind L.,
RA Mitchell W.P., Olinger L., Tatusov R.L., Zhao Q., Koonin E.V., Davis R.W.;
RT "Genome sequence of an obligate intracellular pathogen of humans: Chlamydia
RT trachomatis.";
RL Science 282:754-759(1998).
CC -!- FUNCTION: Inclusion membrane protein probably involved in early
CC modification events of the chlamydial inclusion.
CC {ECO:0000250|UniProtKB:B0B9M3}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:B0B9M3}. Host
CC vacuole, host pathogen-containing vacuole, host pathogen-containing
CC vacuole membrane {ECO:0000250|UniProtKB:B0B9M3}; Multi-pass membrane
CC protein {ECO:0000255}. Note=Secreted, probably by a type III secretion
CC system (By similarity). Localized in the inclusion membrane (By
CC similarity). {ECO:0000250|UniProtKB:B0B9M3}.
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DR EMBL; AE001273; AAC67706.1; -; Genomic_DNA.
DR PIR; F71555; F71555.
DR RefSeq; NP_219618.1; NC_000117.1.
DR RefSeq; WP_009871462.1; NC_000117.1.
DR AlphaFoldDB; P0DJI3; -.
DR IntAct; P0DJI3; 4.
DR MINT; P0DJI3; -.
DR STRING; 813.O172_00625; -.
DR EnsemblBacteria; AAC67706; AAC67706; CT_115.
DR GeneID; 884060; -.
DR KEGG; ctr:CT_115; -.
DR PATRIC; fig|272561.5.peg.126; -.
DR HOGENOM; CLU_139635_0_0_0; -.
DR OMA; LCYKTAG; -.
DR Proteomes; UP000000431; Chromosome.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0140221; C:pathogen-containing vacuole membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR035117; IncD.
DR Pfam; PF17628; IncD; 1.
PE 3: Inferred from homology;
KW Host membrane; Membrane; Reference proteome; Secreted; Transmembrane;
KW Transmembrane helix; Virulence.
FT CHAIN 1..141
FT /note="Inclusion membrane protein D"
FT /id="PRO_0000084198"
FT TRANSMEM 38..58
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 141 AA; 14929 MW; B2E52A45B7537DAD CRC64;
MTKVYANSIQ QERVVDRIAL LERCLDPSNS LPTAKRLVAV AVATILAVAL LVVAGLLFSG
VLCSPVSVLA ASLFFGVGAF LLGGALVGGV LTTEAVTRER LHRSQTLMWN NLCCKTAEVE
QKISTASANA KSNDKTRKLG E