INH_PHOLL
ID INH_PHOLL Reviewed; 134 AA.
AC Q7N8R2;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Alkaline proteinase inhibitor;
DE AltName: Full=PrtA-specific inhibitor;
DE Flags: Precursor;
GN Name=inh; Synonyms=prtI; OrderedLocusNames=plu0656;
OS Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 /
OS TT01).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Photorhabdus.
OX NCBI_TaxID=243265;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15139 / CIP 105565 / TT01;
RX PubMed=14528314; DOI=10.1038/nbt886;
RA Duchaud E., Rusniok C., Frangeul L., Buchrieser C., Givaudan A.,
RA Taourit S., Bocs S., Boursaux-Eude C., Chandler M., Charles J.-F.,
RA Dassa E., Derose R., Derzelle S., Freyssinet G., Gaudriault S., Medigue C.,
RA Lanois A., Powell K., Siguier P., Vincent R., Wingate V., Zouine M.,
RA Glaser P., Boemare N., Danchin A., Kunst F.;
RT "The genome sequence of the entomopathogenic bacterium Photorhabdus
RT luminescens.";
RL Nat. Biotechnol. 21:1307-1313(2003).
CC -!- FUNCTION: Inhibitor of the alkaline protease. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the protease inhibitor I38 family.
CC {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX571861; CAE12951.1; -; Genomic_DNA.
DR AlphaFoldDB; Q7N8R2; -.
DR SMR; Q7N8R2; -.
DR STRING; 243265.plu0656; -.
DR EnsemblBacteria; CAE12951; CAE12951; plu0656.
DR KEGG; plu:plu0656; -.
DR eggNOG; ENOG50334WG; Bacteria.
DR HOGENOM; CLU_155270_0_0_6; -.
DR OMA; PEGSIWS; -.
DR Proteomes; UP000002514; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR InterPro; IPR022815; Inh.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR PRINTS; PR01274; MPTASEINHBTR.
DR SUPFAM; SSF50882; SSF50882; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Metalloenzyme inhibitor; Metalloprotease inhibitor;
KW Periplasm; Protease inhibitor; Reference proteome; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..134
FT /note="Alkaline proteinase inhibitor"
FT /id="PRO_0000026715"
FT DISULFID 50..73
FT /evidence="ECO:0000250"
SQ SEQUENCE 134 AA; 14760 MW; 6C48006258128825 CRC64;
MVFAAWYLKF AGFVALIFSI IGGSMASSLV LPHASELKGV WQLSDKHQQC DVLLTDHPLP
EGSIWSLNGD NDCLAYMFGE VPAGWRPTPD GLTITDEQGS GLAFFAHEPD GWFARFADGR
ELMIKPNKTS KKNE