INH_PSEBN
ID INH_PSEBN Reviewed; 140 AA.
AC Q9KGS7; F2KG66;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Alkaline proteinase inhibitor;
DE Flags: Precursor;
GN Name=inh; Synonyms=aprI; ORFNames=PSEBR_a2822;
OS Pseudomonas brassicacearum (strain NFM421).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=994484;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=NFM421;
RX PubMed=11222613; DOI=10.1128/jb.183.6.2117-2120.2001;
RA Chabeaud P., de Groot A., Bitter W., Tommassen J., Heulin T., Achouak W.;
RT "Phase-variable expression of an operon encoding extracellular alkaline
RT protease, a serine protease homolog, and lipase in Pseudomonas
RT brassicacearum.";
RL J. Bacteriol. 183:2117-2120(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NFM421;
RX PubMed=21515771; DOI=10.1128/jb.00411-11;
RA Ortet P., Barakat M., Lalaouna D., Fochesato S., Barbe V., Vacherie B.,
RA Santaella C., Heulin T., Achouak W.;
RT "Complete genome sequence of a beneficial plant root-associated bacterium,
RT Pseudomonas brassicacearum.";
RL J. Bacteriol. 193:3146-3146(2011).
CC -!- FUNCTION: Inhibitor of the alkaline protease.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the protease inhibitor I38 family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AEA69122.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF286062; AAF87589.1; -; mRNA.
DR EMBL; CP002585; AEA69122.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_003201773.1; NC_015379.1.
DR AlphaFoldDB; Q9KGS7; -.
DR SMR; Q9KGS7; -.
DR STRING; 994484.PSEBR_a2822; -.
DR MEROPS; I38.001; -.
DR EnsemblBacteria; AEA69122; AEA69122; PSEBR_a2822.
DR GeneID; 57259442; -.
DR KEGG; pba:PSEBR_a2822; -.
DR HOGENOM; CLU_155270_1_0_6; -.
DR OrthoDB; 2006069at2; -.
DR Proteomes; UP000006692; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0008191; F:metalloendopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR InterPro; IPR021140; Inh/Omp19.
DR InterPro; IPR016085; Protease_inh_b-brl_dom.
DR Pfam; PF02974; Inh; 1.
DR SUPFAM; SSF50882; SSF50882; 1.
PE 2: Evidence at transcript level;
KW Metalloenzyme inhibitor; Metalloprotease inhibitor; Periplasm;
KW Protease inhibitor; Signal.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..140
FT /note="Alkaline proteinase inhibitor"
FT /id="PRO_0000026718"
SQ SEQUENCE 140 AA; 15267 MW; 95E0B2761C7E03C9 CRC64;
MPSSVQATAG LLATLMMFCG EVAMARSLLL AEPSQLAGQW QAVLSSPQDN AQTQAMQDKP
SNSCLVELKV DQTLGGQTDC LGQWLGDEPV RWFTEPDGLS LIGKQDSRTH LGLRQGDHYQ
MTLKSGLILR LERNKSQSAH