ID   INI1_SCHPO              Reviewed;         117 AA.
AC   Q9UTB8;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 130.
DE   RecName: Full=Pre-mRNA-splicing factor ini1;
GN   Name=ini1; ORFNames=SPAC23H3.02c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=14762117; DOI=10.1242/jcs.00946;
RA   Oltra E., Verde F., Werner R., D'Urso G.;
RT   "A novel RING-finger-like protein Ini1 is essential for cell cycle
RT   progression in fission yeast.";
RL   J. Cell Sci. 117:967-974(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Required for pre-mRNA splicing.
CC       {ECO:0000269|PubMed:14762117}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:14762117}.
CC   -!- SIMILARITY: Belongs to the PHF5 family. {ECO:0000305}.
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DR   EMBL; AY279206; AAP30040.1; -; mRNA.
DR   EMBL; CU329670; CAB40798.2; -; Genomic_DNA.
DR   PIR; T38295; T38295.
DR   RefSeq; NP_593792.1; NM_001019221.2.
DR   AlphaFoldDB; Q9UTB8; -.
DR   SMR; Q9UTB8; -.
DR   BioGRID; 278334; 8.
DR   STRING; 4896.SPAC23H3.02c.1; -.
DR   iPTMnet; Q9UTB8; -.
DR   PaxDb; Q9UTB8; -.
DR   PRIDE; Q9UTB8; -.
DR   EnsemblFungi; SPAC23H3.02c.1; SPAC23H3.02c.1:pep; SPAC23H3.02c.
DR   GeneID; 2541843; -.
DR   KEGG; spo:SPAC23H3.02c; -.
DR   PomBase; SPAC23H3.02c; ini1.
DR   VEuPathDB; FungiDB:SPAC23H3.02c; -.
DR   eggNOG; KOG1705; Eukaryota.
DR   HOGENOM; CLU_110369_2_0_1; -.
DR   InParanoid; Q9UTB8; -.
DR   OMA; AYYCWEC; -.
DR   PhylomeDB; Q9UTB8; -.
DR   PRO; PR:Q9UTB8; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0071011; C:precatalytic spliceosome; IBA:GO_Central.
DR   GO; GO:0005686; C:U2 snRNP; IDA:PomBase.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IDA:PomBase.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR005345; PHF5.
DR   PANTHER; PTHR13120; PTHR13120; 1.
DR   Pfam; PF03660; PHF5; 1.
DR   PIRSF; PIRSF016468; PHF5; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..117
FT                   /note="Pre-mRNA-splicing factor ini1"
FT                   /id="PRO_0000218721"
SQ   SEQUENCE   117 AA;  13267 MW;  D3C877687656E6ED CRC64;
     MSKHHPDLVL CRRQPGITVG KLCERCDEKC PICDSHVRPT TLVRICDECA FGSSQDRCII
     CGAPGVSDCY YCSECTRMEY DRDGCPRVIN LGSSRTDWFY ERKKFKNAGK EMPGATY