INP2_YEAS7
ID INP2_YEAS7 Reviewed; 705 AA.
AC A6ZMM2;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 03-AUG-2022, entry version 40.
DE RecName: Full=Inheritance of peroxisomes protein 2;
GN Name=INP2; ORFNames=SCY_4338;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Required for peroxisome inheritance. Acts as the peroxisome-
CC specific receptor for the myosin V motor MYO2 (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Interacts with MYO2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Peroxisome membrane {ECO:0000250}; Single-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the INP2 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAFW02000021; EDN64096.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZMM2; -.
DR SMR; A6ZMM2; -.
DR PRIDE; A6ZMM2; -.
DR EnsemblFungi; EDN64096; EDN64096; SCY_4338.
DR HOGENOM; CLU_024345_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0005779; C:integral component of peroxisomal membrane; IEA:InterPro.
DR GO; GO:0045033; P:peroxisome inheritance; IEA:InterPro.
DR InterPro; IPR026235; INP2.
DR PRINTS; PR02104; INPROXISOME2.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Peroxisome; Receptor; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..705
FT /note="Inheritance of peroxisomes protein 2"
FT /id="PRO_0000308735"
FT TRANSMEM 215..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 79
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 275
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 343
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 344
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 379
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 517
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 569
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 574
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 705 AA; 81504 MW; 0970D520DB3E3885 CRC64;
MTTNSRPSAL QAPGLQIFSM LKSSEEDGFM SSSLTLDSDN IIGVTENNRQ EFYSTWRKPS
LLSSRSVLHE YSPTIVGSND STFSPITVGK TTKFFNWDDI ISRIFMQQPF GVTHQFFEEF
RYSIITSHFL NDMNHYRLSL HLDQSIMNFH KSSTLLKNVP PKSVPFMATK YGKLAVVEDK
KLYFRQNFNY LSMIITSYRV LTQLKKYCRR KNSPGLKRVV ILILVAVYLS IQQEYFRRHL
ICYKTLLKVR KVLESLQQVD VMIHKYHLRF KEIKNHSFIS RVSLISIADE HSSVIKELLV
FSSDALFYKL KSIIPDIVIF SDTSELSKYC ELYGIDVPNL YYNNTTTVKD LDGKLYRLKL
LKKFMLCCLL SLDMAGNENL SNVNMRNALN KIFPDYMARV QLKKKYNPIG TFQNIVSLLR
GLHSLLSTVL VSLNDHKQIL YAFPEETSTN TGCERANVCS FSKNDKLFQA LNYLKMIENN
LLAIDIRNGI TENDRNIIED KLEELITFWK TSKICGNISR IQKVSPTNTI NHGFHLDILK
GRKSPRSSSV QGLSLERKVD FIDVAESVND SFENDTELEE YEDYDCQEEC SAGSRQNHRV
DFIGKDNCRK PDFKQLSDNE LRRKLDERIL KLAQENREGR ERLRTAKSFE LLRKAQASMS
VKFGFQKPLR DDAFLESRPL SKCKVSSEET IPFLYELKGL LGNDS