ID   INSA1_ECOLI             Reviewed;          91 AA.
AC   P0CF07; P03827; P0ADH0; P0C650; Q2EER2; Q2MCF5; Q2MCH2; Q933I5;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Insertion element IS1 1 protein InsA;
DE   AltName: Full=IS1a;
GN   Name=insA1; OrderedLocusNames=b0022, JW0021;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=375010; DOI=10.1007/bf00271673;
RA   Johnsrud L.;
RT   "DNA sequence of the transposable element IS1.";
RL   Mol. Gen. Genet. 169:213-218(1979).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=1849492; DOI=10.1016/0378-1119(91)90096-t;
RA   Umeda M., Ohtsubo E.;
RT   "Four types of IS1 with differences in nucleotide sequence reside in the
RT   Escherichia coli K-12 chromosome.";
RL   Gene 98:1-5(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA   Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA   Mizobuchi K., Nakata A.;
RT   "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT   2.4 min region.";
RL   Nucleic Acids Res. 20:3305-3308(1992).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Absolutely required for transposition of IS1.
CC   -!- SIMILARITY: Belongs to the IS1 elements InsA family. {ECO:0000305}.
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DR   EMBL; J01729; AAA96228.1; -; Genomic_DNA.
DR   EMBL; X52534; CAA36770.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC73133.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76034.1; -; Genomic_DNA.
DR   PIR; B93826; IEECB9.
DR   PIR; JN0134; JN0134.
DR   RefSeq; NP_414563.1; NC_000913.3.
DR   RefSeq; NP_416408.1; NC_000913.3.
DR   RefSeq; NP_417901.1; NC_000913.3.
DR   RefSeq; YP_001816554.1; NC_010558.1.
DR   RefSeq; YP_001816567.1; NC_010558.1.
DR   RefSeq; YP_002527490.1; NC_011964.1.
DR   RefSeq; YP_003937745.1; NC_014615.1.
DR   RefSeq; YP_004422909.1; NC_015472.1.
DR   RefSeq; YP_444026.1; NC_007675.1.
DR   RefSeq; YP_444042.1; NC_007675.1.
DR   AlphaFoldDB; P0CF07; -.
DR   STRING; 511145.b0022; -.
DR   PaxDb; P0CF07; -.
DR   DNASU; 948449; -.
DR   EnsemblBacteria; AAC73133; AAC73133; b0022.
DR   EnsemblBacteria; BAE76034; BAE76034; BAE76034.
DR   GeneID; 945800; -.
DR   GeneID; 947950; -.
DR   GeneID; 948449; -.
DR   KEGG; ecj:JW0021; -.
DR   KEGG; eco:b0022; -.
DR   KEGG; eco:b1894; -.
DR   KEGG; eco:b3444; -.
DR   EchoBASE; EB4701; -.
DR   eggNOG; COG3677; Bacteria.
DR   HOGENOM; CLU_076276_6_3_6; -.
DR   InParanoid; P0CF07; -.
DR   OMA; NEACAHR; -.
DR   PhylomeDB; P0CF07; -.
DR   BioCyc; EcoCyc:G6086-MON; -.
DR   PRO; PR:P0CF07; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IMP:EcoCyc.
DR   InterPro; IPR024431; InsA_HTH_dom.
DR   InterPro; IPR003220; InsA_N_dom.
DR   Pfam; PF12759; HTH_Tnp_IS1; 1.
DR   Pfam; PF03811; Zn_Tnp_IS1; 1.
PE   3: Inferred from homology;
KW   DNA recombination; Reference proteome; Transposable element; Transposition.
FT   CHAIN           1..91
FT                   /note="Insertion element IS1 1 protein InsA"
FT                   /id="PRO_0000075393"
SQ   SEQUENCE   91 AA;  9868 MW;  8249588966B91FC5 CRC64;
     MASVSISCPS CSATDGVVRN GKSTAGHQRY LCSHCRKTWQ LQFTYTASQP GTHQKIIDMA
     MNGVGCRATA RIMGVGLNTI LRHLKNSGRS R