ID   INSA4_ECOLI             Reviewed;          91 AA.
AC   P0CF10; P03827; P0ADH0; P0C651; Q2EER2; Q2MCF5; Q2MCH2; Q933I5;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Insertion element IS1 4 protein InsA;
DE   AltName: Full=IS1d;
GN   Name=insA4; OrderedLocusNames=b4516, JW0971;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=1849492; DOI=10.1016/0378-1119(91)90096-t;
RA   Umeda M., Ohtsubo E.;
RT   "Four types of IS1 with differences in nucleotide sequence reside in the
RT   Escherichia coli K-12 chromosome.";
RL   Gene 98:1-5(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Absolutely required for transposition of IS1.
CC   -!- SIMILARITY: Belongs to the IS1 elements InsA family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X52536; CAA36772.1; -; Genomic_DNA.
DR   EMBL; U00096; ABD18646.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35753.1; -; Genomic_DNA.
DR   PIR; B93826; IEECB9.
DR   PIR; JN0134; JN0134.
DR   RefSeq; NP_414799.1; NC_000913.3.
DR   RefSeq; NP_414809.1; NC_000913.3.
DR   RefSeq; NP_862965.1; NC_004998.1.
DR   RefSeq; NP_863031.1; NC_004998.1.
DR   RefSeq; NP_957637.1; NC_005327.1.
DR   RefSeq; YP_001096420.1; NC_009133.1.
DR   RefSeq; YP_001096518.1; NC_009133.1.
DR   RefSeq; YP_001816581.1; NC_010558.1.
DR   RefSeq; YP_001816635.1; NC_010558.1.
DR   RefSeq; YP_002527566.1; NC_011964.1.
DR   RefSeq; YP_003108318.1; NC_013122.1.
DR   RefSeq; YP_006953891.1; NC_019090.1.
DR   RefSeq; YP_006954228.1; NC_019095.1.
DR   RefSeq; YP_006990704.1; NC_019424.1.
DR   RefSeq; YP_007447506.1; NC_020278.2.
DR   RefSeq; YP_009071497.1; NC_025183.1.
DR   RefSeq; YP_588445.1; NC_000913.3.
DR   AlphaFoldDB; P0CF10; -.
DR   DIP; DIP-16998N; -.
DR   EnsemblBacteria; ABD18646; ABD18646; b4516.
DR   EnsemblBacteria; BAA35753; BAA35753; BAA35753.
DR   GeneID; 1450250; -.
DR   GeneID; 944946; -.
DR   GeneID; 944951; -.
DR   KEGG; ecj:JW0971; -.
DR   KEGG; eco:b0265; -.
DR   KEGG; eco:b0275; -.
DR   KEGG; eco:b4516; -.
DR   PATRIC; fig|511145.12.peg.1023; -.
DR   HOGENOM; CLU_076276_6_3_6; -.
DR   InParanoid; P0CF10; -.
DR   OMA; ASITIHC; -.
DR   PhylomeDB; P0CF10; -.
DR   BioCyc; EcoCyc:MON0-4228; -.
DR   PRO; PR:P0CF10; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IBA:GO_Central.
DR   InterPro; IPR024431; InsA_HTH_dom.
DR   InterPro; IPR003220; InsA_N_dom.
DR   Pfam; PF12759; HTH_Tnp_IS1; 1.
DR   Pfam; PF03811; Zn_Tnp_IS1; 1.
PE   3: Inferred from homology;
KW   DNA recombination; Reference proteome; Transposable element; Transposition.
FT   CHAIN           1..91
FT                   /note="Insertion element IS1 4 protein InsA"
FT                   /id="PRO_0000393352"
SQ   SEQUENCE   91 AA;  9902 MW;  8249502B66B91FC5 CRC64;
     MASVSISCPS CSATDGVVRN GKSTAGHQRY LCSHCRKTWQ LQFTYTASQP GTHQKIIDMA
     MNGVGCRATA RIMGVGLNTI FRHLKNSGRS R