ID   INSC1_ECOLI             Reviewed;         121 AA.
AC   P0CF40; O07989; O08018; O08019; P0C5W2; P19776; P76357; P77346; Q2MBI5;
AC   Q2MC65; Q79BJ2; Q9JMT0;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 57.
DE   RecName: Full=Transposase InsC for insertion element IS2A;
GN   Name=insC1; OrderedLocusNames=b0360, JW0351;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RA   Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M.,
RA   Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D.,
RA   Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.;
RT   "Sequence of minutes 4-25 of Escherichia coli.";
RL   Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS2.
CC   -!- SIMILARITY: Belongs to the transposase 8 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB18084.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAE76141.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U73857; AAB18084.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC73463.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76141.1; ALT_INIT; Genomic_DNA.
DR   PIR; B65240; B65240.
DR   RefSeq; NP_414894.2; NC_000913.3.
DR   RefSeq; NP_415921.2; NC_000913.3.
DR   RefSeq; NP_417338.3; NC_000913.3.
DR   RefSeq; NP_417516.3; NC_000913.3.
DR   RefSeq; NP_418692.2; NC_000913.3.
DR   RefSeq; YP_026163.2; NC_000913.3.
DR   AlphaFoldDB; P0CF40; -.
DR   SMR; P0CF40; -.
DR   STRING; 316407.1736667; -.
DR   PaxDb; P0CF40; -.
DR   PRIDE; P0CF40; -.
DR   EnsemblBacteria; AAC73463; AAC73463; b0360.
DR   EnsemblBacteria; BAE76141; BAE76141; BAE76141.
DR   GeneID; 945025; -.
DR   GeneID; 945967; -.
DR   GeneID; 946455; -.
DR   GeneID; 947347; -.
DR   GeneID; 947520; -.
DR   GeneID; 948781; -.
DR   KEGG; ecj:JW0351; -.
DR   KEGG; eco:b0360; -.
DR   KEGG; eco:b1403; -.
DR   KEGG; eco:b1997; -.
DR   KEGG; eco:b2861; -.
DR   KEGG; eco:b3044; -.
DR   KEGG; eco:b4272; -.
DR   EchoBASE; EB4751; -.
DR   eggNOG; COG2963; Bacteria.
DR   HOGENOM; CLU_027402_25_0_6; -.
DR   InParanoid; P0CF40; -.
DR   PhylomeDB; P0CF40; -.
DR   BioCyc; EcoCyc:G6212-MON; -.
DR   PRO; PR:P0CF40; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002514; Transposase_8.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01527; HTH_Tnp_1; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..121
FT                   /note="Transposase InsC for insertion element IS2A"
FT                   /id="PRO_0000075409"
SQ   SEQUENCE   121 AA;  13452 MW;  59431E5C452E067A CRC64;
     MIDVLGPEKR RRRTTQEKIA IVQQSFEPGM TVSLVARQHG VAASQLFLWR KQYQEGSLTA
     VAAGEQVVPA SELAAAMKQI KELQRLLGKK TMENELLKEA VEYGRAKKWI AHAPLLPGDG
     E