ID   INSC6_ECOLI             Reviewed;         121 AA.
AC   P0CF45; O07989; O08018; O08019; P0C5W2; P19776; P76357; P77346; Q2MBI5;
AC   Q2MC65; Q79BJ2; Q9JMT0;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Transposase InsC for insertion element IS2K;
GN   Name=insC6; OrderedLocusNames=b4272, JW4229;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7610040; DOI=10.1093/nar/23.12.2105;
RA   Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome VI: DNA sequence of the region
RT   from 92.8 through 100 minutes.";
RL   Nucleic Acids Res. 23:2105-2119(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS2.
CC   -!- SIMILARITY: Belongs to the transposase 8 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA97168.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=BAE78268.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U14003; AAA97168.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC77228.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE78268.1; ALT_INIT; Genomic_DNA.
DR   PIR; B65240; B65240.
DR   RefSeq; NP_414894.2; NC_000913.3.
DR   RefSeq; NP_415921.2; NC_000913.3.
DR   RefSeq; NP_417338.3; NC_000913.3.
DR   RefSeq; NP_417516.3; NC_000913.3.
DR   RefSeq; NP_418692.2; NC_000913.3.
DR   RefSeq; YP_026163.2; NC_000913.3.
DR   AlphaFoldDB; P0CF45; -.
DR   SMR; P0CF45; -.
DR   EnsemblBacteria; AAC77228; AAC77228; b4272.
DR   EnsemblBacteria; BAE78268; BAE78268; BAE78268.
DR   GeneID; 945025; -.
DR   GeneID; 945967; -.
DR   GeneID; 946455; -.
DR   GeneID; 947347; -.
DR   GeneID; 947520; -.
DR   GeneID; 948781; -.
DR   KEGG; ecj:JW4229; -.
DR   KEGG; eco:b0360; -.
DR   KEGG; eco:b1403; -.
DR   KEGG; eco:b1997; -.
DR   KEGG; eco:b2861; -.
DR   KEGG; eco:b3044; -.
DR   KEGG; eco:b4272; -.
DR   PATRIC; fig|511145.12.peg.1466; -.
DR   EchoBASE; EB4711; -.
DR   HOGENOM; CLU_027402_25_0_6; -.
DR   InParanoid; P0CF45; -.
DR   PhylomeDB; P0CF45; -.
DR   BioCyc; EcoCyc:MON0-4254; -.
DR   PRO; PR:P0CF45; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002514; Transposase_8.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF01527; HTH_Tnp_1; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
PE   3: Inferred from homology;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..121
FT                   /note="Transposase InsC for insertion element IS2K"
FT                   /id="PRO_0000393453"
SQ   SEQUENCE   121 AA;  13452 MW;  59431E5C452E067A CRC64;
     MIDVLGPEKR RRRTTQEKIA IVQQSFEPGM TVSLVARQHG VAASQLFLWR KQYQEGSLTA
     VAAGEQVVPA SELAAAMKQI KELQRLLGKK TMENELLKEA VEYGRAKKWI AHAPLLPGDG
     E