ID   INSD8_ECOLI             Reviewed;         218 AA.
AC   P0CF60; P0C5W4; P19777; P76167; P76916; P77033; Q79EJ0;
DT   20-APR-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Putative transposase InsD for insertion element IS2E;
GN   Name=insD8; OrderedLocusNames=b1578, JW1570;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Involved in the transposition of the insertion sequence IS2.
CC   -!- CAUTION: Could be the product of a pseudogene. IS2E is a partial IS2
CC       sequence which lacks the N-terminal 83 residues of InsD. Locus b1578 is
CC       not annotated in the MG1655 genome and b1578/JW1570 is probably not
CC       expressed. {ECO:0000305}.
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DR   EMBL; U00096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP009048; BAA15283.2; -; Genomic_DNA.
DR   AlphaFoldDB; P0CF60; -.
DR   EnsemblBacteria; BAA15283; BAA15283; BAA15283.
DR   KEGG; ecj:JW1570; -.
DR   eggNOG; COG2801; Bacteria.
DR   HOGENOM; CLU_052819_0_0_6; -.
DR   InParanoid; P0CF60; -.
DR   PhylomeDB; P0CF60; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0032196; P:transposition; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   5: Uncertain;
KW   DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW   Transposition.
FT   CHAIN           1..218
FT                   /note="Putative transposase InsD for insertion element
FT                   IS2E"
FT                   /id="PRO_0000393579"
FT   DOMAIN          23..206
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ   SEQUENCE   218 AA;  24724 MW;  37C547ABD90AD05C CRC64;
     MPAINAKRVY RIMRQNALLL ERKPAVPPSK RAHTGRVAVK ESNQRWCSDG FEFCCDNGER
     LRVTFALDCC DREALHWAVT TGGFNSETVQ DVMLGAVERR FGNDLPSSPV EWLTDNGSCY
     RANETRQFAR MLGLEPKNTA VRSPESNGIA ESFVKTIKRD YISIMPKPDG LTAAKNLAEA
     FEHYNEWHPH SALGYRSPRE YLRQRACNGL SDNRCLEI