ID   APOC4_BOVIN             Reviewed;         127 AA.
AC   Q3SYR5;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Apolipoprotein C-IV;
DE            Short=Apo-CIV;
DE            Short=ApoC-IV;
DE   AltName: Full=Apolipoprotein C4;
DE   Flags: Precursor;
GN   Name=APOC4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Testis;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May participate in lipoprotein metabolism. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the liver and secreted in plasma.
CC   -!- SIMILARITY: Belongs to the apolipoprotein C4 family. {ECO:0000305}.
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DR   EMBL; BC103430; AAI03431.1; -; mRNA.
DR   RefSeq; NP_001029979.1; NM_001034807.1.
DR   AlphaFoldDB; Q3SYR5; -.
DR   STRING; 9913.ENSBTAP00000027391; -.
DR   PaxDb; Q3SYR5; -.
DR   PRIDE; Q3SYR5; -.
DR   Ensembl; ENSBTAT00000027391; ENSBTAP00000027391; ENSBTAG00000020556.
DR   GeneID; 618041; -.
DR   KEGG; bta:618041; -.
DR   CTD; 346; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020556; -.
DR   VGNC; VGNC:52177; APOC4.
DR   eggNOG; ENOG502TE52; Eukaryota.
DR   GeneTree; ENSGT00390000015914; -.
DR   HOGENOM; CLU_161459_0_0_1; -.
DR   InParanoid; Q3SYR5; -.
DR   OMA; KWQWFWG; -.
DR   OrthoDB; 1563324at2759; -.
DR   TreeFam; TF336879; -.
DR   Proteomes; UP000009136; Chromosome 18.
DR   Bgee; ENSBTAG00000020556; Expressed in liver and 30 other tissues.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IBA:GO_Central.
DR   GO; GO:0034361; C:very-low-density lipoprotein particle; IBA:GO_Central.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IBA:GO_Central.
DR   GO; GO:0070328; P:triglyceride homeostasis; IBA:GO_Central.
DR   InterPro; IPR028120; APOC4.
DR   PANTHER; PTHR32288; PTHR32288; 1.
DR   Pfam; PF15119; APOC4; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Lipid transport; Reference proteome; Secreted; Signal;
KW   Transport.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000250|UniProtKB:P55057"
FT   CHAIN           28..127
FT                   /note="Apolipoprotein C-IV"
FT                   /id="PRO_0000042968"
FT   CARBOHYD        63
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   127 AA;  14438 MW;  7062F2291728EA9D CRC64;
     MSFPGCRPQA LASLCFCVLV LACVVACQQE EPEGTLSPQP APARSSWSLV PGKVKEWVEP
     LVNRTREKWK WFWGPTAFRG FMETYYDDHL KDLGSRARAW LRSSKDNLLN KAHSLCPQLL
     CRPSDQN