INSL1_ECOLI
ID INSL1_ECOLI Reviewed; 370 AA.
AC P0CF91; P08409; P11307; P76952; P77426; Q2MCH6; Q47051;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 18-MAY-2010, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Putative transposase InsL for insertion sequence element IS186A;
GN Name=insL1; OrderedLocusNames=b0016, JW0015;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2996940; DOI=10.1016/0014-5793(85)80040-5;
RA Chong P., Hui I., Loo T., Gillam S.;
RT "Structural analysis of a new GC-specific insertion element IS186.";
RL FEBS Lett. 192:47-52(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2997142; DOI=10.1128/jb.164.2.957-959.1985;
RA Kothary R.K., Jones D., Candido E.P.M.;
RT "IS186: an Escherichia coli insertion element isolated from a cDNA
RT library.";
RL J. Bacteriol. 164:957-959(1985).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=1630901; DOI=10.1093/nar/20.13.3305;
RA Yura T., Mori H., Nagai H., Nagata T., Ishihama A., Fujita N., Isono K.,
RA Mizobuchi K., Nakata A.;
RT "Systematic sequencing of the Escherichia coli genome: analysis of the 0-
RT 2.4 min region.";
RL Nucleic Acids Res. 20:3305-3308(1992).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Involved in the transposition of the insertion sequence
CC IS186.
CC -!- SIMILARITY: Belongs to the transposase 11 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; X03123; CAA26900.1; -; Genomic_DNA.
DR EMBL; M11300; AAA25030.1; -; Genomic_DNA.
DR EMBL; U00096; AAC73127.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76030.1; -; Genomic_DNA.
DR PIR; G65013; QQEC47.
DR RefSeq; NP_414557.1; NC_000913.3.
DR RefSeq; NP_415114.1; NC_000913.3.
DR RefSeq; NP_416895.2; NC_000913.3.
DR RefSeq; WP_001300563.1; NZ_STEB01000093.1.
DR AlphaFoldDB; P0CF91; -.
DR STRING; 511145.b0016; -.
DR PaxDb; P0CF91; -.
DR PRIDE; P0CF91; -.
DR EnsemblBacteria; AAC73127; AAC73127; b0016.
DR EnsemblBacteria; BAE76030; BAE76030; BAE76030.
DR GeneID; 57431685; -.
DR GeneID; 944754; -.
DR GeneID; 945200; -.
DR GeneID; 946896; -.
DR KEGG; ecj:JW0015; -.
DR KEGG; eco:b0016; -.
DR KEGG; eco:b0582; -.
DR KEGG; eco:b2394; -.
DR EchoBASE; EB4748; -.
DR eggNOG; COG3385; Bacteria.
DR HOGENOM; CLU_049434_1_0_6; -.
DR InParanoid; P0CF91; -.
DR OMA; EIHIADR; -.
DR BioCyc; EcoCyc:G6083-MON; -.
DR PRO; PR:P0CF91; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002559; Transposase_11.
DR Pfam; PF01609; DDE_Tnp_1; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
PE 3: Inferred from homology;
KW DNA recombination; DNA-binding; Reference proteome; Transposable element;
KW Transposition.
FT CHAIN 1..370
FT /note="Putative transposase InsL for insertion sequence
FT element IS186A"
FT /id="PRO_0000173294"
FT CONFLICT 121
FT /note="A -> G (in Ref. 2; AAA25030)"
FT /evidence="ECO:0000305"
FT CONFLICT 126
FT /note="S -> T (in Ref. 2; AAA25030)"
FT /evidence="ECO:0000305"
FT CONFLICT 354..370
FT /note="QPSLDFPPRSAGSEKKN -> SHRWISPPEVPDPKRRT (in Ref. 1;
FT CAA26900)"
FT /evidence="ECO:0000305"
FT CONFLICT 354..370
FT /note="QPSLDFPPRSAGSEKKN -> SHRWISPPEVRIRKEEL (in Ref. 2;
FT AAA25030)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 370 AA; 40909 MW; FDD2041F5F3D7F03 CRC64;
MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY GPGGMSLREV
TAWAQLHDVA TLSDVALLKR LRNAADWFGI LAAQTLAVRA AVTGCTSGKR LRLVDGTAIS
APGGGSAEWR LHMGYDPHTC QFTDFELTDS RDAERLDRFA QTADEIRIAD RGFGSRPECI
RSLAFGEADY IVRVHWRGLR WLTAEGMRFD MMGFLRGLDC GKNGETTVMI GNSGNKKAGA
PFPARLIAVS LPPEKALISK TRLLSENRRK GRVVQAETLE AAGHVLLLTS LPEDEYSAEQ
VADCYRLRWQ IELAFKRLKS LLHLDALRAK EPELAKAWIF ANLLAAFLID DIIQPSLDFP
PRSAGSEKKN
