ID   INSL_VIGUN              Reviewed;          51 AA.
AC   P83770;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2004, sequence version 1.
DT   02-DEC-2020, entry version 48.
DE   RecName: Full=Insulin-like protein;
DE   Contains:
DE     RecName: Full=Insulin-like protein B chain;
DE   Contains:
DE     RecName: Full=Insulin-like protein A chain;
DE   Flags: Fragments;
OS   Vigna unguiculata (Cowpea).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Vigna.
OX   NCBI_TaxID=3917 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Epace-10 {ECO:0000269|PubMed:12937781};
RX   PubMed=12937781; DOI=10.1590/s0100-879x2003000900004;
RA   Venancio T.M., Oliveira A.E.A., Silva L.B., Machado O.L.T.,
RA   Fernandes K.V.S., Xavier-Filho J.;
RT   "A protein with sequence homology to bovine insulin is found in the legume
RT   Vigna unguiculata (cowpea).";
RL   Braz. J. Med. Biol. Res. 36:1167-1173(2003).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RC   STRAIN=cv. Epace-10;
RA   Venancio T.M.;
RL   Thesis (2004), Universidade Estadual do Norte Fluminense, Brazil.
RN   [3] {ECO:0000305}
RP   REVIEW.
RA   Xavier-Filho J., Oliveira A.E.A., Silva L.B., Azevedo C.R., Venancio T.M.,
RA   Machado O.L.T., Oliva M.L., Fernandes K.V.S., Xavier-Neto J.;
RT   "Plant insulin or glucokinin: a conflicting issue.";
RL   Braz. J. Plant Physiol. 15:67-78(2003).
CC   -!- FUNCTION: May be involved in the transport of sugars to the developing
CC       embryo in the fruit. May also be involved in signaling events.
CC       {ECO:0000303|PubMed:12937781}.
CC   -!- TISSUE SPECIFICITY: Expressed in seed coats and pods.
CC       {ECO:0000269|PubMed:12937781, ECO:0000269|Ref.2, ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in developing fruits between 4 and 20
CC       days after pollination. Concentration decreases when fruits ripen.
CC       {ECO:0000269|PubMed:12937781, ECO:0000269|Ref.2, ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the insulin family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd04367; IlGF_insulin_like; 1.
DR   InterPro; IPR004825; Insulin.
DR   InterPro; IPR016179; Insulin-like.
DR   PANTHER; PTHR11454; PTHR11454; 1.
DR   Pfam; PF00049; Insulin; 1.
DR   PRINTS; PR00277; INSULIN.
DR   SMART; SM00078; IlGF; 1.
PE   1: Evidence at protein level;
KW   Carbohydrate metabolism; Direct protein sequencing; Glucose metabolism;
KW   Sugar transport; Transport.
FT   PEPTIDE         1..30
FT                   /note="Insulin-like protein B chain"
FT                   /id="PRO_0000016229"
FT   PEPTIDE         31..51
FT                   /note="Insulin-like protein A chain"
FT                   /id="PRO_0000016230"
FT   NON_CONS        30..31
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   51 AA;  5771 MW;  7417A9EBD667D6B0 CRC64;
     FVNQHLXGSH LVEALYLVXG ERGFFYTPKA GIVEQXXASV XSLYQLENYX N