APOC4_CHLSB
ID APOC4_CHLSB Reviewed; 127 AA.
AC A0A0D9S1R4;
DT 03-JUL-2019, integrated into UniProtKB/Swiss-Prot.
DT 27-MAY-2015, sequence version 1.
DT 03-AUG-2022, entry version 22.
DE RecName: Full=Apolipoprotein C-IV;
DE Short=Apo-CIV;
DE Short=ApoC-IV;
DE AltName: Full=Apolipoprotein C4;
DE Flags: Precursor;
GN Name=APOC4;
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP IDENTIFICATION.
RA Puppione D.L.;
RL Unpublished observations (APR-2019).
CC -!- FUNCTION: May participate in lipoprotein metabolism. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the apolipoprotein C4 family. {ECO:0000305}.
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DR EMBL; AQIB01135957; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01135958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01135959; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007995348.1; XM_007997157.1.
DR AlphaFoldDB; A0A0D9S1R4; -.
DR STRING; 60711.ENSCSAP00000014803; -.
DR Ensembl; ENSCSAT00000001272; ENSCSAP00000014803; ENSCSAG00000003243.
DR GeneID; 103234842; -.
DR KEGG; csab:103234842; -.
DR CTD; 346; -.
DR eggNOG; ENOG502TE52; Eukaryota.
DR GeneTree; ENSGT00390000015914; -.
DR OMA; KWQWFWG; -.
DR OrthoDB; 1563324at2759; -.
DR BioGRID-ORCS; 103234842; 0 hits in 6 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 6.
DR Bgee; ENSCSAG00000003243; Expressed in liver and 3 other tissues.
DR GO; GO:0034364; C:high-density lipoprotein particle; IEA:Ensembl.
DR GO; GO:0034361; C:very-low-density lipoprotein particle; IEA:Ensembl.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IEA:Ensembl.
DR GO; GO:0070328; P:triglyceride homeostasis; IEA:Ensembl.
DR InterPro; IPR028120; APOC4.
DR PANTHER; PTHR32288; PTHR32288; 1.
DR Pfam; PF15119; APOC4; 1.
PE 3: Inferred from homology;
KW Lipid transport; Reference proteome; Secreted; Signal; Transport.
FT SIGNAL 1..27
FT /evidence="ECO:0000250|UniProtKB:P55057"
FT CHAIN 28..127
FT /note="Apolipoprotein C-IV"
FT /id="PRO_5002346276"
SQ SEQUENCE 127 AA; 14635 MW; 215C747940B67EC3 CRC64;
MSLLRNRLQD LPALCLCVLV LACIGACQSE AYEGTPSPPP KLKMSHWSLV TGRMKELLEP
VVNRTRDRWQ WFWSPSTFRG FMQTYYDDHL RDLGPRTKAW LLKSKESLLN KTHSLCPRIV
CGDKDQG