APOC4_PAPAN
ID APOC4_PAPAN Reviewed; 127 AA.
AC A0A096P2H6;
DT 07-JUN-2017, integrated into UniProtKB/Swiss-Prot.
DT 26-NOV-2014, sequence version 1.
DT 03-AUG-2022, entry version 28.
DE RecName: Full=Apolipoprotein C-IV;
DE Short=Apo-CIV;
DE Short=ApoC-IV;
DE AltName: Full=Apolipoprotein C4;
DE Flags: Precursor;
GN Name=APOC4;
OS Papio anubis (Olive baboon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Papio.
OX NCBI_TaxID=9555;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Liu Y.L., Abraham K.A., Akbar H.A., Ali S.A., Anosike U.A., Aqrawi P.A.,
RA Arias F.A., Attaway T.A., Awwad R.A., Babu C.B., Bandaranaike D.B.,
RA Battles P.B., Bell A.B., Beltran B.B., Berhane-Mersha D.B., Bess C.B.,
RA Bickham C.B., Bolden T.B., Carter K.C., Chau D.C., Chavez A.C.,
RA Clerc-Blankenburg K.C., Coyle M.C., Dao M.D., Davila M.L.D.,
RA Davy-Carroll L.D., Denson S.D., Dinh H.D., Fernandez S.F., Fernando P.F.,
RA Forbes L.F., Francis C.F., Francisco L.F., Fu Q.F., Garcia-Iii R.G.,
RA Garrett T.G., Gross S.G., Gubbala S.G., Hirani K.H., Hogues M.H.,
RA Hollins B.H., Jackson L.J., Javaid M.J., Jhangiani S.J., Johnson A.J.,
RA Johnson B.J., Jones J.J., Joshi V.J., Kalu J.K., Khan N.K., Korchina V.K.,
RA Kovar C.K., Lago L.L., Lara F.L., Le T.-K.L., Lee S.L., Legall-Iii F.L.,
RA Lemon S.L., Liu J.L., Liu Y.-S.L., Liyanage D.L., Lopez J.L.,
RA Lorensuhewa L.L., Mata R.M., Mathew T.M., Mercado C.M., Mercado I.M.,
RA Morales K.M., Morgan M.M., Munidasa M.M., Ngo D.N., Nguyen L.N.,
RA Nguyen T.N., Nguyen N.N., Obregon M.O., Okwuonu G.O., Ongeri F.O.,
RA Onwere C.O., Osifeso I.O., Parra A.P., Patil S.P., Perez A.P., Perez Y.P.,
RA Pham C.P., Pu L.-L.P., Puazo M.P., Quiroz J.Q., Rouhana J.R., Ruiz M.R.,
RA Ruiz S.-J.R., Saada N.S., Santibanez J.S., Scheel M.S., Schneider B.S.,
RA Simmons D.S., Sisson I.S., Tang L.-Y.T., Thornton R.T., Tisius J.T.,
RA Toledanes G.T., Trejos Z.T., Usmani K.U., Varghese R.V., Vattathil S.V.,
RA Vee V.V., Walker D.W., Weissenberger G.W., White C.W., Williams A.W.,
RA Woodworth J.W., Wright R.W., Zhu Y.Z., Han Y.H., Newsham I.N.,
RA Nazareth L.N., Worley K.W., Muzny D.M., Rogers J.R., Gibbs R.G.;
RT "Whole genome assembly of Papio anubis.";
RL Submitted (MAR-2012) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP IDENTIFICATION.
RA Puppione D.L.;
RL Unpublished observations (APR-2017).
CC -!- FUNCTION: May participate in lipoprotein metabolism. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the apolipoprotein C4 family. {ECO:0000305}.
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DR EMBL; JH682906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009196974.1; XM_009198710.2.
DR AlphaFoldDB; A0A096P2H6; -.
DR STRING; 9555.ENSPANP00000019551; -.
DR GeneID; 101020716; -.
DR KEGG; panu:101020716; -.
DR CTD; 346; -.
DR eggNOG; ENOG502TE52; Eukaryota.
DR HOGENOM; CLU_161459_0_0_1; -.
DR OMA; KWQWFWG; -.
DR OrthoDB; 1563324at2759; -.
DR Proteomes; UP000028761; Chromosome 20.
DR Bgee; ENSPANG00000024334; Expressed in liver and 45 other tissues.
DR GO; GO:0034364; C:high-density lipoprotein particle; IEA:Ensembl.
DR GO; GO:0034361; C:very-low-density lipoprotein particle; IEA:Ensembl.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR GO; GO:0010890; P:positive regulation of sequestering of triglyceride; IEA:Ensembl.
DR GO; GO:0070328; P:triglyceride homeostasis; IEA:Ensembl.
DR InterPro; IPR028120; APOC4.
DR PANTHER; PTHR32288; PTHR32288; 1.
DR Pfam; PF15119; APOC4; 1.
PE 3: Inferred from homology;
KW Lipid transport; Reference proteome; Secreted; Signal; Transport.
FT SIGNAL 1..27
FT /evidence="ECO:0000250|UniProtKB:P55057"
FT CHAIN 28..127
FT /note="Apolipoprotein C-IV"
FT /id="PRO_5001923239"
SQ SEQUENCE 127 AA; 14663 MW; 263EF19E22339EC3 CRC64;
MSLLRNRLQD LPALCLCVLV LACIGACQSE AYEGTPSPPP KLKMSHWSLV TGRMKELLEP
VLKRTRDRWQ WFWSPSTFRG FMQTYYDDHL RDLGPRTKAW LLKSKESLLN KTHSLCPRIV
CGDKDQG