ID   INT10_DICDI             Reviewed;         991 AA.
AC   Q552Q3; Q75K30;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Integrator complex subunit 10-like protein;
GN   ORFNames=DDB_G0275707;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May be a component of the Integrator complex, a complex
CC       involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and
CC       in their 3'-box-dependent processing. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFI02000013; EAL69604.1; -; Genomic_DNA.
DR   RefSeq; XP_643628.1; XM_638536.1.
DR   AlphaFoldDB; Q552Q3; -.
DR   PaxDb; Q552Q3; -.
DR   EnsemblProtists; EAL69604; EAL69604; DDB_G0275707.
DR   GeneID; 8620215; -.
DR   KEGG; ddi:DDB_G0275707; -.
DR   dictyBase; DDB_G0275707; -.
DR   eggNOG; ENOG502SY21; Eukaryota.
DR   HOGENOM; CLU_301577_0_0_1; -.
DR   InParanoid; Q552Q3; -.
DR   OMA; ARNDYFD; -.
DR   PRO; PR:Q552Q3; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..991
FT                   /note="Integrator complex subunit 10-like protein"
FT                   /id="PRO_0000344381"
FT   REGION          180..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          310..345
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          462..484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          549..614
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          961..991
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        964..991
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   991 AA;  115960 MW;  40A6914247F2AF3B CRC64;
     MMVDNEEINS LSIENILERI NKSSNINEAK SLCLFASSLF DNNQYLLIQR YLISIKERDF
     DISIQLFWRL FNNNSFKEYI VLVVLKFLEK EIEDLEYYDF IKKNYRDQFQ KIFIDSDDNS
     TNNSSSSSNE NKKNKRSYLK LNTILNKLTK SLNHLSFYIS EIDNLNKFFN PITFLLNNNN
     NNNNNNNNNN NNNNNKNNSN NNNKNNNNNN DDSNNNNNNN FLKILELIQK SCQYLNENEN
     YEYSILLYLL IKGKFENKIR TFIKSSKKED QDIKSKIKRF WFNGIQSLNQ YKNKYSSKIE
     IEPPLPMKSY FDEDDYDQKQ QQQQQQQQQQ QEQKGSKEDE EDIEKQKKSL TSEIELFLLP
     INRFCLPIIF HIENEEFEQL DIKGNSGSGS DSSSSISKLE IVDQCWKYYI CKGDDITDES
     ILEIQKFLQQ FADSGKHLKR HQNNSILNFT INLLSNPEKA RNDYFDRNSE GNGGDENDEN
     SQESNDSYEF EIHLGIYLLS SLLYISSWRY FKFLVTGSSN IEKQNIQTIG TLKKNQILLF
     DANFNSNSNS SSGSNGIINN NSNSNQQSYH NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN
     NNNNNNNNNQ GQQPNLSMIT HQVLYYSNVD DESSFDDEFP KIVFTKQQTE AIKHLTLCME
     CFNDLNQEPW INDFKRILST TWNNSKFYWL YNSLADSHYY YKLDGANTLI PIGDSKKRLF
     NPNDELWFNR LLLNIGMTNH SEIEDSIICL LEILISISIP PPPSSSSSSF SSSNSSLNND
     LFNQQLVPSK HTFKTIKPYL TVFSEEEILF WCIDTLATCY ERLGMVGEIT VLYQAYWNYY
     KSRFYQIINE IKGTPNQNPN LIPLSNLVKK DLQIGYFFPR FFDYIINIEM LEEFCFILNK
     GFKLDILQRN QTVSSNREMI DIIKRHITIT TSNNNLTIPI LLKQFFNEEL DHFLIKKENR
     EKQYSSSNTA NNSGVNNSPI HNQNTDVEMN E