ID   INT3_DROER              Reviewed;        1072 AA.
AC   B3N449;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Integrator complex subunit 3 homolog;
DE   AltName: Full=SOSS complex subunit A homolog;
GN   Name=IntS3; ORFNames=GG23122;
OS   Drosophila erecta (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7220;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14021-0224.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the Integrator subunit 3 family. {ECO:0000305}.
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DR   EMBL; CH954177; EDV59943.1; -; Genomic_DNA.
DR   RefSeq; XP_001970884.1; XM_001970848.2.
DR   AlphaFoldDB; B3N449; -.
DR   SMR; B3N449; -.
DR   STRING; 7220.FBpp0141668; -.
DR   EnsemblMetazoa; FBtr0143176; FBpp0141668; FBgn0115275.
DR   GeneID; 6543033; -.
DR   KEGG; der:6543033; -.
DR   eggNOG; KOG4262; Eukaryota.
DR   HOGENOM; CLU_007659_0_0_1; -.
DR   OMA; LCHEDNI; -.
DR   OrthoDB; 644334at2759; -.
DR   PhylomeDB; B3N449; -.
DR   Proteomes; UP000008711; Unassembled WGS sequence.
DR   InterPro; IPR045334; INTS3.
DR   InterPro; IPR019333; INTS3_N.
DR   PANTHER; PTHR13587; PTHR13587; 1.
DR   Pfam; PF10189; Ints3_N; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein.
FT   CHAIN           1..1072
FT                   /note="Integrator complex subunit 3 homolog"
FT                   /id="PRO_0000385308"
FT   REGION          920..941
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1002..1072
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1044..1072
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1042
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1043
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1047
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1048
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1072 AA;  124228 MW;  ED82BB2E3D9E388B CRC64;
     MEQQQSKNNA HVSKLFVCTA VDCKDDIEEK FERSFVTLQM QISGLSDKEM HDMLSQAVCK
     DKQHEEISIG FLYIMLTDPS MAPKTYRDVT LVSRDGMNGI VTNLTFLVAE KYTKLTEVAR
     RQLIWLLREF VKHQVLSVEN VIWNCLRQAG GGDVSSRNLF LIESLLDIFI EFRTWLEGNP
     FLVQSTVYSF VRLIEDHANP ALMSLRQKEV KFTISLIRER FHDIIPLGRD FVRLLQNVAR
     IPEFEQLWRD ILFNPKILNQ TFNGIWQLLH IRTSRRFLQC RLLPEMERKI SFLASSVKFG
     NQKRYQDWFQ EKYFATPESH SLRSDLIRFI INVIHPTNDM LCSDIIPRWA IIGWLISSCT
     NPIASANAKL SLFYDWLFFD PAKDNIMNIE PGILVMYHSI RNHPFVSSTL LDFLCRITKN
     FFVKHEDKIR IGVYNSLKLI LEKQVIPNLQ PLFESPKLDR ELRNLIRDNF REFLSPPANL
     GQLLYPSTHT VQGHILKKES DQRILHCENA DLHETGLINI SGTVISVVDE DKKISLVPTD
     QEIESVFSDG TAENLRRVHN IDENTDDDDD LPLSKVRLKE KPRVELADAI AESFESFVSK
     RNSYTWEAFL KDFRPLPASA FEEFQLNYVI SNTVLILRET LPQQNIFSES KTDEKHLAKS
     ISYPLYGLFR FLYENDEKSK KPFQILLSEI CERIPEIGYL LLYFMKIYCK LQTRKNSQQS
     YQFKTTIYRQ ICDAADEKIA NCLLRDLDML EKENTNIFLW LLPDIYREFK SIATNNTDLL
     RITLRCIDAR NVRDILYSVA QGKLTIFKQD GLIDCIRESL EFETYEQFCL WQIVQAHDVP
     LRCIQDLLPE LEAGSHPEAL SHFLLLLKNE EPTNEIIRLM LSREPKSKGD PFVTSALRFW
     CQRYEEKLSE IIASLLTSKY PSSSPNKRKR PPKGISVSTS IPSADQVLNH LEHYRRSCRH
     GTGTGLYVHD MMQRALQSAY SHSNDSTKKQ FSDLFALAAE EDTTVGRRGG SGRGRKQPGS
     KKDVNNHGTS KKTAEMVKTI YSSDENSSEE DWSKSKITQT AKRRKKANND SD