ID   INT3_DROMO              Reviewed;        1079 AA.
AC   B4KJ11;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Integrator complex subunit 3 homolog;
DE   AltName: Full=SOSS complex subunit A homolog;
GN   Name=IntS3; ORFNames=GI18256;
OS   Drosophila mojavensis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15081-1352.22;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the Integrator subunit 3 family. {ECO:0000305}.
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DR   EMBL; CH933807; EDW13524.1; -; Genomic_DNA.
DR   RefSeq; XP_002004082.2; XM_002004046.2.
DR   AlphaFoldDB; B4KJ11; -.
DR   SMR; B4KJ11; -.
DR   STRING; 7230.FBpp0167473; -.
DR   EnsemblMetazoa; FBtr0168981; FBpp0167473; FBgn0140995.
DR   eggNOG; KOG4262; Eukaryota.
DR   HOGENOM; CLU_007659_0_0_1; -.
DR   InParanoid; B4KJ11; -.
DR   OMA; LCHEDNI; -.
DR   PhylomeDB; B4KJ11; -.
DR   Proteomes; UP000009192; Unassembled WGS sequence.
DR   InterPro; IPR045334; INTS3.
DR   InterPro; IPR019333; INTS3_N.
DR   PANTHER; PTHR13587; PTHR13587; 1.
DR   Pfam; PF10189; Ints3_N; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..1079
FT                   /note="Integrator complex subunit 3 homolog"
FT                   /id="PRO_0000385311"
FT   REGION          544..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          925..949
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1010..1079
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1036..1050
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1051..1079
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1049
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1050
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1054
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1055
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1079 AA;  124292 MW;  5E053EBF9588EA72 CRC64;
     MEQQQQKSAV HVSKLFVCTA VDCKDEIEEK FERSYASLQQ QIAGLSDKEM HDMLTQFVCK
     EKQHEEISIG FLYIILTDPA MAPKTYRDIT LVSRDGMNVI VANLTLLVAE KYTKLTETAR
     RQLIWVLREF VKHQVLSVEN VIWNCLRQAG GGDVSHKNLF LVESLLDIFI EYRAWLETNP
     FLVQSSVYSF VRLIEDHANP ALISLRQKEV KFTISLIRDR FHDIIPLGRD FVRLLQNVAR
     IPEFEQLWRD ILYNPKSLHP TFNGIWHLLQ IRTSRRFLQC RLLPEMERKL HFLASSVKFG
     NQKRYQDWFQ DKYFATPESH SLRSDLIRFI INVIHPTNDM LCSDIIPRWA IIGWLISSCT
     NPIASANAKL SLFYDWLFFD PAKDNIMNIE PGILVMYHSI RNHPFVSSTL LDFLCRITKN
     FYIKNEDKIR LGVYNSLKLI LDKQVIPNLH PLFESPKLDR ELRNLIRENF REFVSPVSNM
     PQTMYPATHS IQAPIFKKEA DQRITQIENI DVGAGVLAAN SSTISLVDDD SKVATIPTES
     LERETEAVFS DEDGENLGRC TKNEENTDDD DDLPLSKVRL KEKPVPEKVE LPEAIAESFE
     IFVTKRNSFT WEAFLKDFRT LPASTLDETQ LNYVISNTVL ILRETLPQQN VFSESKTEEK
     CLAKSISYPL YGLFRFLYEN EDKSKKPFQS LLSEICERLS ETGYLLLYFM KIHCKLQTRK
     NAQQSYQFKT TVYRQICEAT DGKIASCLVR DLDLLEKENT TIYLWLLPDI YREFKTIAIN
     NTDLLRITLR CVDAKNVRDI MYSIAQGKMT IFKQDGLIEC IRESLEYETY EQFCLWQLIQ
     AHDVPLKCIQ DILPELEAAN HPEALSHLLL LLKNEEPTNE IIRLLLSREA KSRGDPFVTS
     ALRFWCQRCE EKLSEIIASL LTSKYPSSSP NKRKRPSKGS SAASSTPSAD HVLNHLEHYR
     RSCRHGTGTG LYVHDMMQRA LQSAYTHSNE STKKQFSDLF ALAAEDETTA VGRRGGSGRG
     RKQPAGKKDS NNHSAGSKKN SDVVKAIYSS DESSSEEDWS KHKITQAAKK RKKAINDSD