ID   INT3_DROVI              Reviewed;        1079 AA.
AC   B4LQY8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Integrator complex subunit 3 homolog;
DE   AltName: Full=SOSS complex subunit A homolog;
GN   Name=IntS3; ORFNames=GJ17515;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- SIMILARITY: Belongs to the Integrator subunit 3 family. {ECO:0000305}.
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DR   EMBL; CH940649; EDW64527.1; -; Genomic_DNA.
DR   RefSeq; XP_002052372.1; XM_002052336.2.
DR   AlphaFoldDB; B4LQY8; -.
DR   SMR; B4LQY8; -.
DR   STRING; 7244.FBpp0231932; -.
DR   EnsemblMetazoa; FBtr0233440; FBpp0231932; FBgn0204685.
DR   GeneID; 6629177; -.
DR   KEGG; dvi:6629177; -.
DR   eggNOG; KOG4262; Eukaryota.
DR   HOGENOM; CLU_007659_0_0_1; -.
DR   InParanoid; B4LQY8; -.
DR   OMA; LCHEDNI; -.
DR   OrthoDB; 644334at2759; -.
DR   PhylomeDB; B4LQY8; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   InterPro; IPR045334; INTS3.
DR   InterPro; IPR019333; INTS3_N.
DR   PANTHER; PTHR13587; PTHR13587; 1.
DR   Pfam; PF10189; Ints3_N; 1.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..1079
FT                   /note="Integrator complex subunit 3 homolog"
FT                   /id="PRO_0000385313"
FT   REGION          539..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          925..949
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1010..1079
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1036..1050
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1051..1079
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1049
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1050
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1054
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         1055
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1079 AA;  124298 MW;  1DE168E8D07CDC9E CRC64;
     MEQQQQKSAA HVSKLFVCTA VDCKDEIEEK FERSYVSLQQ QIAGLSDKEM HDMLTQIVCK
     EKQHEEISIG FLYIILTDPA MAPKTYRDIT LVSRDGMNVI VANLTLLVAE KYAKLTETAR
     RQLIWVLREF VKHQVLSVEN VIWNCLRQAG GGDVSHKNLF LVESLLDIFI EYRAWLEAIP
     FLVQSSVYSF VRLIEDHANP ALMPLRQKEV KFTISLIRDR FQDIIPLGRD FVRLLQNVAR
     IPEFELLWRD ILCNPKSLHP TFNGIWHLLQ IRTSRRFLQC RLLPEMERKL HFLASSVKFG
     NQKRYQDWFQ DKYFATPESH SLRSDLIRFI INVIHPTNDM LCSDIIPRWA IIGWLISSCT
     NPIASANAKL SLFYDWLFFD PAKDNIMNIE PGILVMYHSI RNHPFVSSTL LDFLCRITKN
     FYIKNEDKIR LGVYNSLKLI LDKQVIPNLH PLFESPKLDR ELRNLIRENF REFVSPVANM
     PQSIYPATHS IQAPIFKKEA DQRMLQSENI DVGSGAFAAN SGTISLVDDD NKIAITPVES
     SERETEAVFS DDDGENIARC NKNDENTDDD DDLPLSKVRL KEKPVPEKVE LPDAIAESFE
     IFVTKRNSFT WEAFLKDFRT LPASTLDETQ LNYVISNTVL ILRETLPQQN VFSESKTEEK
     YLAKSISYPL YGLFRFLYEN EDKSKKPFQT LLSEICERLS ETGYLLLYFM KIHCKLQTRK
     NAQQSYQFKT TVYRQICEAT DEKIGICLVR DLDLLEKENT TIYLWLLPDI YREFKTIAIN
     NTDLLRITLR CVDAKNVRDI MYSIAQGKLT IFKQDGLIDC IRESLEYETY EQFCLWQLIQ
     AHDVPLKCIQ DILPELEAAN HPEALSHLLL LLKNEEPTSE IIRLLLSREA KTRGDPFVTS
     ALRFWCQRCE EKLSEIIASL LTSKYPSSSP NKRKRPSKGS SAASSTPSAD HVLNHLEHYR
     RSCRHGTGTG LYVHDMMQRA LQSAYSHSNE STKKQFSDLF ALAAEDETTA VGRRGGSGRG
     RKQPVGKKDS NNHNAGSKKN SDVVKTIYSS DENSSEEDWS KHKITQAAKK RKKAINDSD